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Printable Handouts
Navigable Slide Index
- Introduction
- Koch's postulates (1882)
- Case
- Clostridium difficile (1)
- Clindamycin associated colitis due to C. difficile
- Clostridium difficile (2)
- C. difficile and the gastrointestinal microbiota
- "Community thinking"
- How to study the gut microbiota?
- 16S rRNA
- Antibiotic-associated diarrhea (AAD)
- Microbial ecology of AAD
- Microbial community associated with AAD
- The enterome and gastrointestinal homeostasis
- C. difficile and antibiotic-associated diarrhea
- Patients/clinical results
- Microbial ecology: diversity
- Collectors curves/rarefaction
- Initial and recurrent C. difficile rarefaction
- C. difficile colitis - microbial ecology insights
- How microbes defend and define us
- Resilience of gut microbial community structure
- Microbial communities in mice
- Microbial response to antibiotic stress (1)
- Microbial response to antibiotic stress (2)
- Microbial community diversity and antibiotics
- C. difficile in model systems
- C. difficile associated disease -a mouse model(1)
- C. difficile associated disease -a mouse model(2)
- Dissecting role of antibiotics
- Two groups of C. difficile treated mice
- A normal mouse colon
- A colon from an animal affected by c. difficile (1)
- An infected animal with a benign response
- A colon from an animal affected by c. difficile (2)
- Colon histopathology difference
- Vero cell cytotoxin assay on tissue
- C. difficile load in tissues
- Differences in microbial communities
- Cefoperazone treatment (1)
- Cefoperazone treatment (2)
- Microbial ecology in cefoperazone treated mice
- Survival in cefoperazone treated mice
- Model
- Summary
- Acknowledgements
Topics Covered
- C. difficile and the antibiotic-associated colitis
- Changes in the microbiota due to antibiotics predisposed to C. difficile infection
- Use of culture-independent techniques to study the gut microbiota
- Antibiotics can have reproducible effects on the gut microbiota
- Animal models and human studies provide insight into the role of the gut microbiota in mediating colonization resistance against C. difficile infection
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Talk Citation
Young, V. (2011, September 27). The microbiota in the development of colitis due to Clostridium difficile infection [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved August 14, 2024, from https://doi.org/10.69645/KKOJ8915.Export Citation (RIS)
Publication History
Financial Disclosures
- Dr. Vincent Young has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
The microbiota in the development of colitis due to Clostridium difficile infection
Published on September 27, 2011
41 min
A selection of talks on Clinical Practice
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