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• 41 min
  1. The clinical syndrome of Alzheimer's disease

  • Dr. Jonathan Schott
• 21 min
  2. Lewy body dementia

  • Prof. John-Paul Taylor
• 43 min
  3. Pathology of Alzheimer's disease

  • Prof. Tamas Revesz
• 35 min
  4. Genetics of early onset Alzheimer's disease

  • Dr. Ekaterina Rogaeva
• 32 min
  5. Thirty years of Alzheimer's genetics: what's new and what's next?

  • Dr. Lars Bertram
• 40 min
  6. Immunotherapy as an approach to treating Alzheimer's disease

  • Prof. David Morgan
• 19 min
  7. Pathogenic mechanisms and therapeutic approaches for the tauopathies

  • Prof. Karen Duff
• 36 min
  8. Vascular factors in Alzheimer's disease

  • Dr. Deborah Gustafson
• 41 min
  9. Neuroimaging markers in AD trials

  • Prof. Nick Fox
• 70 min
  10. Imaging amyloid: now that we can see it, what does it all mean?

  • Prof. William Klunk
• 51 min
  11. Metabolic and biochemical alterations in Alzheimer's disease: facts and fictions

  • Prof. Mark A. Smith
• 54 min
  12. Abeta toxicity 1

  • Prof. Colin L. Masters
• 28 min
  13. Abeta toxicity 2

  • Prof. Colin L. Masters
• 43 min
  14. Alzheimer's disease: where are we up to?

  • Prof. John Hardy
• 53 min
  15. ApoE4 - the most prevalent genetic risk factor for Alzheimer's disease

  • Prof. Daniel Michaelson
• Archived Lectures *These may not cover the latest advances in the field
• 29 min
  16. Lewy body dementia

  • Prof. Ian McKeith

Printable Handouts

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Navigable Slide Index

1. Introduction
2. Aims of the lecture
3. Epidemiology of Alzheimer's disease (AD)
4. Alzheimer's disease progression
5. Molecular mechanism of Alzheimer's disease
6. Histopathology of Alzheimer's disease
7. Braak and Braak AD staging
8. Cell death reflected by progressive atrophy
9. Current criteria for Alzheimer's disease
10. What does the patient complain of? (1)
11. What does the patient complain of? (2)
12. Typical Alzheimer's disease
13. The symptoms of disease progression
14. Atypical Alzheimer's disease (1)
15. A scan of biparietal Alzheimer's disease
16. Atypical Alzheimer's disease (2)
17. Familial Alzheimer's disease
18. Clinical assessment
19. Clinical approach (1)
20. Clinical approach (2)
21. Assessing cognition
22. Observing patient's behaviour
23. Mini-mental state examination (1)
24. Mini-mental state examination (2)
25. Testing cognition - other instruments
26. Bedside neuropsychometric testing (1)
27. Cognitive tests (1)
28. Cognitive tests (2)
29. Bedside neuropsychometric testing (2)
30. Examination
31. Investigations
32. Formal neuropsychological testing
33. Structural neuroimaging (1)
34. Structural neuroimaging (2)
35. Other diagnostics
36. Treatment options (1)
37. Treatment options (2)
38. Other issues
39. Can we diagnose AD earlier?
40. Individual's journey through AD
41. Mild cognitive impairment
42. Biomarkers aid prediction of conversion
43. CSF A-beta reduction and total tau elevation
44. Revising criteria for the diagnosis of AD
45. Effects of disease prevention
46. Pathological changes predate symptoms
47. Summary

Topics Covered

• Epidemiology
• Disease progression
• Molecular mechanism
• Histopathology
• Braak and Braak AD staging
• Cell death and atrophy
• Disease criteria
• Typical disease
• Atypical disease
• Biparietal Alzheimer's disease
• Familial Alzheimer's disease
• Assessing cognition
• Observing patient's behaviour
• Mini-mental state examination
• Bedside neuropsychometric testing
• Formal neuropsychological testing
• Structural neuroimaging
• Treatment options
• Biomarkers
• Disease prevention

Links

Series:

• Alzheimer's Disease

Categories:

• Clinical Practice
• Neuroscience

Therapeutic Areas:

• Neurology

Talk Citation

Publication History

• Published on March 28, 2011

Financial Disclosures

• Dr. Jonathan Schott has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.