Topics Covered
- Reversible protein phosphorylation
- Classification of protein phosphatases
- Protein tyrosine phosphatase family, structure of PTP1B, catalytic mechanism, basis for pTyr specificity, recognition of IRK, regulation by ROS and cyclic sulphenamide
- Dual specificity phosphatases
- Eya protein tyrosine phosphatases
- PPP family of Ser/Thr phosphatases, structure of PP1, catalytic mechanism, inhibition by okadaic acid and microcystin, targeting subunits, PP2A, PP2B, PP5
- PPM family of Ser/Thr phosphatases, structure, catalytic mechanism
- Summary
Links
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Talk Citation
Barford, D. (2010, November 30). Structure and mechanisms of protein phosphatases [Video file]. In
The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved May 24, 2022, from
https://hstalks.com/bs/1883/.
Publication History
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Published on November 30, 2010
Financial Disclosures
- Prof. David Barford has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.