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Printable Handouts
Navigable Slide Index
- Introduction
- A two way relationship
- Virus and autoimmunity
- The hepatitis C virus
- Mixed cryoglobulinemia
- Etiology - meta-analysis
- Etiology - etiological studies
- Autoimmune manifestations
- HCV and autoimmune diseases
- Sjogren's syndrome and HCV
- 35 SS HCV patients
- Systemic lupus erythematosus and HCV
- Subset of SLE-HCV patients
- Polyarteritis nodosa and HCV
- Antiphospholipid syndrome and HCV
- Prevalence of HCV infection in patients with APS
- Prevalence of antiphospholipid antibodies
- Profiles of patients with anti-HCV Abs
- HCV systemic autoimmune diseases prevalence
- HCV triple tropism
- Virus and autoimmunity - HIV
- Autoimmune diseases in HIV patients
- HIV and autoimmunity
- HIV and autoimmunity: stage description
- HIV and autoimmunity: autoantibodies
- Autoimmune response versus CD4 count
- Clinical features related to APS
- APS-related features in chronic viral patients
- APS and HCV patients vs. APS and HIV patients
- Features in chronic infected APS vs. APS only
- APS and infections: molecular mimicry
- APS and infections
- APS and infections - general characteristics
- APS and infections - manifestations of APS (1)
- APS and infections - manifestations of APS (2)
- APS and infections - associated infections
- Catastrophic APS (CAPS)
- Molecular mimicry: CAPS
- The "CAPS" registry (1)
- Clinical manifestations of CAPS patients
- The "CAPS" registry (2)
- CAPS registry: precipitating factors
- The role of infection in CAPS pathogesis
- APS infectious origin
- Prevalence of aCL antibodies in different infections
- Beta-2-glycoprotein-1
- APS antibodies detected in diverse infections (1)
- APS antibodies detected in diverse infections (2)
- Abs against beta-2GPI-related peptides
- Different peptide Abs and specific clinical features
- Eular prize 2005
- MI/stroke risks after acute infection/vaccination
- A two way relationship (2)
- "Everything is autoimmune until proven otherwise"
- "Everything is autoimmune and infectious"
Topics Covered
- Viruses and autoimmunity
- The role of HCV and HIV
- Antiphospholipid syndrome and infections
- Molecular mimicry
- Infectious agents and antibodies to beta-2-glycoprotein I peptides
Links
Series:
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Therapeutic Areas:
Talk Citation
Cervera, R. (2017, May 17). Infection and autoimmunity: a two-way relationship [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 12, 2024, from https://doi.org/10.69645/UAVY3575.Export Citation (RIS)
Publication History
Financial Disclosures
- Dr. Ricard Cervera has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Infection and autoimmunity: a two-way relationship
A selection of talks on Microbiology
Transcript
Please wait while the transcript is being prepared...
0:00
Hello, I am Ricard Cervera.
And I am consultant at
the Department of Autoimmune Diseases
at the Hospital Clinic in Barcelona, Catalonia in Spain.
And I am going to talk, in the next minutes,
on infection and autoimmunity.
Some think that we believe it is a two-way relationship.
0:22
And why do we believe that this is a two-way relationship?
Well, the relationship between autoimmunity and infection is certainly well-known.
We all know that patients with autoimmune diseases have many infections.
In other words, patients with
autoimmune diseases are prone to develop infectious diseases,
infections that range from mild to very severe infections.
However, what is certainly very interesting and certainly challenging,
is the possibility that infection can develop autoimmunity.
Or in other words,
that the origin, the cause,
the etiology of autoimmune diseases can be an infection.
And, in the next few minutes,
we are certainly going to talk mainly on this specific aspect,
that is the possibility that an infectious agent produce an autoimmune disease.
And we will talk on two specific aspects.
First, the already known relation between virus and autoimmunity.
And second, the most challenging new hypothesis,
the hypothesis of the antiphospholipid syndrome infections
origin through molecular mimicry.
Let us start with the first aspect,
the relationship between virus and autoimmunity.