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Printable Handouts
Navigable Slide Index
- Introduction
- Epigenetics makes the difference
- Nearly all human diseases are heritable
- Human diseases: simple and complex (1)
- Human diseases: simple and complex (2)
- Chromosome: it is not only DNA
- Epigenetic definition
- Epigenetics: regulation of genomic activities
- Epigenetic factors contribute to the phenotype
- Some epigenetic factors can be inherited
- Unlike DNA, epigenetic factors can be modified
- Epigenetic misregulation explain complex disease
- Enrichment of differentially methylated fractions
- Application of microarrays for epiG studies
- Epigenomic studies of twins
- DZ exhibit more epigenetic differences than MZ
- Large intra-individual variability of methylation
- Epigenetic heritability
- The molecular basis of heritability
- Epigenetic changes in major psychosis (1)
- Epigenetic changes in major psychosis (2)
- Less methylation in schizophrenic patients
- Partial correlation network analysis
- Epigenetic differences: cause or effect?
- Genetics/epigenetics and disease: 2004-2011
- Acknowledgement
Topics Covered
- Complex disease
- Non-mendelian features
- Epigenetic heritability
- Partial epigenetic stability
- Inherited and acquired epigenetic misregulation of genes and genomes
- Microarrays and epigenomic profiles in health and disease
Talk Citation
Petronis, A. (2010, July 1). Epigenomics of complex disease [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved November 7, 2024, from https://doi.org/10.69645/TIRZ5574.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Art Petronis has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.