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Printable Handouts
Navigable Slide Index
- Introduction
- Overview
- Prevalence
- Neary criteria
- Variants of FTD
- Tau positive and tau negative variants
- Tau immunopositive inclusions
- Inclusions in sporadic ALS
- Is FTD genetic?
- Progranulin a new FTD gene
- Progranulin haploinsufficiency
- VBM analysis of FTLD with progranulin mutations
- Progranulin gene structure
- Progranulin highly expressed in peripheral blood
- The syndrome
- The region
- The circuit
- Cells, molecules and genes
- FTD atrophy by clinical stage
- Von Economo neuron (VENs) ACC and FI
- VENs
- Vens: vulnerable neuron in FTD?
- Regions unique to individual behaviors
- Overeating in FTD
- Evolution of the "self"
- Development of self - mirror studies
- Development of self
- Startle in FTD
- Traditional frontal neuropsychology
- Amyloid imaging
- Research criteria for FTD
- Conclusions
- Acknowledgements
Topics Covered
- Prevalence and nomenclature of FTD
- The pathology of FTD (tau, TDP-43)
- The genetics of FTD (tau, progranulin)
- Patterns of atrophy and neuroanatomical correlates of behavior and cognition
- von Economo neurons
- Neuroimaging (amyloid imaging)
- Treatment
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Talk Citation
Miller, B. (2010, February 14). Frontotemporal dementia [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 7, 2024, from https://doi.org/10.69645/MHXQ2297.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Bruce Miller has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.