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1. Introduction
2. The forensic genetics research group
3. Forensic genetics
4. DNA typing in forensic analysis
5. DNA profiling/ typing
6. Types of DNA variations
7. Detection of minisatellites
8. Overcoming the problem with PCR and STRs
9. Short tandem repeats (STRs)
10. New techniques in the field
11. Commercially available multiplexes
12. Paternity testing
13. Commonly used STR loci
14. Different STR sets in use
15. MiniSTRs
16. Strategies for substituting STRs
17. The DNA analysis procedure in forensics
18. Laboratory intelligence management systems
19. Automation
20. New markers in the field
21. Mitochondrial DNA (mtDNA)
22. mtDNA analysis in forensic genetics
23. The use of small overlapping fragments
24. mtDNA haplogroups
25. The EMPOP database
26. Inheritance properties of the Y chromosome
27. Commercial Y STR kits
28. Y chromosome haplotype reference database
29. SNPs essential for defining Y haplogroups
30. STRs in the X chromosome
31. Advantages of SNPs
32. The SNP for ID consortium
33. Specific criteria for SNP selection
34. SNP frequencies estimates
35. Forensic validation in critical samples
36. SNP typing applications
37. Usage of SNPS in complicated paternity cases
38. Prediction of geographic origin of samples
39. Ancestry assignment for different SNP panels
40. 3D plots
41. Ancestry analysis in the Madrid 11-M bombing (1)
42. Ancestry analysis in the Madrid 11-M bombing (2)
43. Identification of genetic markers
44. Physical traits of the suspect
45. DNA databases
46. Standardization of forensic DNA analysis
47. The importance of DNA statistics
48. The forensic craftsman vs. the forensic scientist
49. Problems that need to be solved
50. Summary

Topics Covered

• DNA typing in forensic analysis
• DNA fingerprinting
• Copy number variants
• Detection of minisatellites using MLPs and SLPs
• Short tandem repeats
• The DNA analysis procedure in forensics
• Advantages of mtDNA analysis over nucDNA
• Applications of mtDNA analysis
• Selecting SNPs
• Forensic validation in critical samples
• SNP typing applications
• Casework application
• DNA databases
• Statistics, interpretation and communication

Links

Series:

• Introduction to Human Genetics

Categories:

• Genetics & Epigenetics
• Methods

Talk Citation

Publication History

• Published on December 28, 2009
• Archived on September 8, 2024

Financial Disclosures

• Dr. Angel Carracedo has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.