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About Biomedical Basics
Biomedical Basics are AI-generated explanations prepared with access to the complete collection, human-reviewed prior to publication. Short and simple, covering biomedical and life sciences fundamentals.
Topics Covered
- Topical vs systemic medications
- Routes of administration
- Mechanisms of action
- Benefits and risks
- Factors affecting absorption & bioavailability
- Potential side effects
- When to use topical vs systemic
- Common uses & limitations
- Clinical decision-making
Talk Citation
(2025, December 31). Topical vs systemic medications [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 31, 2025, from https://doi.org/10.69645/ITSM7366.Export Citation (RIS)
Publication History
- Published on December 31, 2025
Financial Disclosures
A selection of talks on Immunology
Transcript
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0:00
This presentation will
examine topical versus
systemic medications
with a focus
on the key differences
between the two,
focusing on how they
are administered,
how they act in the body,
and their respective
benefits and risks.
We will discuss situations
where one approach is
preferred over the
other based on disease
characteristics and patient needs.
Additionally, we will examine
factors affecting
drug absorption,
bioavailability,
and potential for side
effects with each type.
Finally, we will highlight
common uses and limitations of
both topical and
systemic therapies
to guide effective
clinical decision-making.
We will explore the
differences between
topical and systemic
medications concepts
that are central to
modern therapeutics.
Topical medications
are applied directly
to a localized area
such as the skin,
eyes or mucous membranes and
are usually intended to
act where they're applied.
In contrast,
systemic medications
are introduced into
the body to be
absorbed and distributed through
the bloodstream affecting cells
or tissues throughout the body.
Knowing when and why to use
each approach is crucial
for maximizing
treatment efficacy
while minimizing side effects.
The main distinction between
these approaches is
the intended reach of
the drug's effect.
Topical medications
target a specific area,
making them ideal for localized
conditions like eczema,
fungal infections
or eye allergies,
offering rapid relief with
minimal systemic exposure.
Systemic medications
such as tablets,