Neuropathology of neurodegenerative disorders
33 min
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- Scope of the Problem
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34 min
1. Cancer pain- Prof. Judith Paice
- Current Therapies
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58 min
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17 min
3. Spinal analgesia for cancer pain- Prof. Jon Raphael
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41 min
4. Celiac plexus block- Prof. David Brown
- Future Directions
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45 min
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36 min
6. Symptom control: using technology pragmatically- Dr. Steven Richeimer
- From Palliative Care to Chronic Pain
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42 min
7. Insight and responsibility: ethics in pain medicine and palliative care- Prof. Rollin Gallagher
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23 min
8. The patient with pain: a palliative care approach- Dr. Janet Abrahm
- Archived Lectures *These may not cover the latest advances in the field
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34 min
9. Cancer pain and related symptoms: an overview- Prof. Judith Paice
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74 min
10. Cancer pain control: an evidence-based approach- Prof. Daniel Carr
- Dr. Baraa Tayeb
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47 min
11. Optimal treatment of chronic pain- Prof. Gordon Irving
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33 min
12. Chronic cancer pain: the price of success?- Prof. Allen Burton
Printable Handouts
Navigable Slide Index
- Introduction
- Overview
- WHO 3-step analgesic ladder (1)
- International survey of cancer pain
- UK national cancer pain survey 2000
- Increase in mod-severe pain 2000-2004
- Cancer pain is endemic in the developed world
- Cancer pain in Norway
- Systematic review of past 40 years (1)
- Systematic review of past 40 years (2)
- Systematic review of past 40 years (3)
- Pain is very common in advanced cancer
- 2007 EPIC survey (1)
- So what has been achieved?
- The problem
- The science of pain mechanisms and pain control
- Cancer pain is complex
- Cancer pain scenarios
- Aetiology of cancer pain
- Chronic pain is mediated by immune mechanisms
- The causes
- 20th century view of cancer care
- WHO cancer pain programme
- Keeping it simple in 1986
- WHO 3-step analgesic ladder (2)
- Who 3-step ladder - systematic review (1)
- Who 3-step ladder - systematic review (2)
- Who 3-step ladder - systematic review (3)
- Validation of WHO ladder
- The ladder and the clock
- What has impeded progress?
- The WHO analgesic ladder - Ferreira 2006
- The WHO analgesic ladder - Eisenberg 2005 (1)
- Starting severe pain patients on oxycodone (1)
- Starting severe pain patients on oxycodone (2)
- Do we need to go through step 2?
- Problems with words
- Adjuvants in pain control
- Molecular mechanism of pain modulation
- Current molecular neurotransmission targets
- Rat model for peripheral neuropathic pain (1)
- Rat model for peripheral neuropathic pain (2)
- Gabapentin for neuropathic cancer pain
- Morphine, gabapentin or their combination (1)
- Morphine, gabapentin or their combination (2)
- The solution
- The WHO analgesic ladder - Eisenberg 2005 (2)
- Mechanism-based ways of treating cancer pain
- Pyramid of modern approaches to cancer pain (1)
- Do anti cancer treatments reduce pain?
- Vertebroplasty for spinal pain
- Family of therapeutic opioids/opiates
- How do opioids reduce pain?
- Are all opioids the same?
- Today's useful opioids
- Mucosal absorption of opioids
- Can opioids do harm?
- Opioid adverse effect
- 2007 EPIC survey (2)
- Opioid therapy for chronic pain (1)
- Opioid therapy for chronic pain (2)
- Opioid tolerance and hyperalgesia (1)
- Opioid tolerance and hyperalgesia (2)
- Downstream intracellular signaling
- The A118G polymorphism in opioid receptor
- Cochrane update on morphine for cancer pain
- EAPC recommendations for opioids 2001
- How good is oral morphine?
- Comparison of morphine and oxycodone
- Fentanyl vs. morphine - systematic review (1)
- Fentanyl vs. morphine - systematic review (2)
- Can opioids be combined?
- Whose choice matters?
- Physician attitudes to cancer pain management (1)
- Physician attitudes to cancer pain management (2)
- Models of pain management: dogma vs. rationality
- What else can we offer besides oral morphine?
- Pyramid of modern approaches to cancer pain (2)
- Comprehensive modern approach to analgesics
- Towards a new mechanism-based approach
Topics Covered
- Who 3-step analgesic ladder for cancer pain
- Overview of WHO cancer pain programme
- Cancer pain: a global problem
- UK national cancer patient survey
- Cancer pain is still endemic in the developed world
- Pain characteristics
- Pain in advanced cancer
- 2007 EPIC survey
- What has been achieved?
- The problem
- The science of pain mechanisms and pain control
- Cancer pain is complex
- Cancer pain scenarios
- Aetiology of cancer pain
- Chronic pain is mediated by immune/inflammatory mechanisms
- The WHO resource allocation model
- Validation of WHO ladder
- What has impeded progress?
- What is an 'adjuvant' in pain control?
- Current molecular neurotransmission targets for pain control
- The solution
- Several mechanism-based ways of treating cancer pain
- Pyramid of modern approaches to cancer pain
- Do anti-cancer treatments reduce pain?
- How do opioids reduce pain and are they all the same?
- Can opioids do harm?
- Morphine for cancer pain
- Can opioids be combined?
- Has the WHO ladder altered physician attitudes to cancer pain management?
- Models of pain management: dogma vs. rationality
- What else can we offer besides oral morphine?
- Comprehensive modern approach to analgesics for cancer pain
- Towards a new mechanism-based approach
Links
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Talk Citation
Ahmedzai, S. (2009, February 23). The rational use of opioid analgesics for cancer pain - with a critique of the WHO 3-step ladder [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved September 1, 2024, from https://doi.org/10.69645/DHDH7929.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Sam Ahmedzai has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
The rational use of opioid analgesics for cancer pain - with a critique of the WHO 3-step ladder
Published on February 23, 2009
58 min
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