Histone modifications and prospects for an epigenetic code.
This talk will give an overview of the wide range
of histone modifications that are now known to exist,
and discuss the possibility that they might operate as an epigenetic code,
something that works in parallel with the genetic code to regulate chromatin function.
I plan to take a historical approach to the subject and explain the origins of
the idea that histone modifications might operate as units of epigenetic information.
By doing this, I hope to be able to illustrate
how a possible epigenetic code might operate,
and what we should expect it to do.