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Printable Handouts
Navigable Slide Index
- Introduction
- Defining what probiotics are and what they are not
- Why probiotics have garnered so much attention
- Reasons for attention to probiotics
- What’s it got to do with the human microbiome?
- Why should you care?
- Guides and evidence for probiotics
- Treatment of premature babies
- Treatment of colic in babies
- Prevention of atopic dermatitis in children
- Upper respiratory infection recovery in children
- Upper respiratory infection recovery in adults
- Lowering the risk of cardiovascular disease
- Relief from irritable bowel syndrome
- Relief from inflammatory bowel disease
- Pediatric gastrointestinal disorders
- Reproductive tract health (and lactation)
- Recurrence of urinary tract infection (UTI)
- Impact of probiotics on lactation
- Competitive exclusion
- Co-aggregation and biosurfactant production
- Bacteriocin and H2O2 and signalling effects
- Immunomodulation
- Modulation of tight junctions
- What exciting areas are emerging?
- Useful additional references
- Final remarks
Topics Covered
- What probiotics are
- Why probiotics garner much attention
- Evidence for positive probiotic effects
- How probiotics work (potential mechanisms)
Talk Citation
Reid, G. (2016, August 31). Probiotics [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 25, 2024, from https://doi.org/10.69645/MZIH9148.Export Citation (RIS)
Publication History
Financial Disclosures
- Dr. Gregor Reid has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
A selection of talks on Microbiology
Transcript
Please wait while the transcript is being prepared...
0:00
Hello, my name is Dr. Gregor Reid.
I'm the Professor of Microbiology
and Immunology and Surgery,
Western University in Canada,
and a scientist at the
Lawson Health Research Institute
in London, Ontario.
0:15
What are probiotics?
The definition is
"live microorganisms
that when administered
in adequate amounts
confer a health benefit
on the host."
And this is from 2001
Food and Agriculture Organization
of the United Nations
and the World Health Organization.
And this definition has stood
the test of time
and is used worldwide.
The photograph on the right
shows a colored version of bacteria
that you would expect to see,
for example, in the intestine,
many different types of organisms.
So what are not probiotics?
Well, they're not in you
unless you have taken them.
In other words, you could have
a blue bacteria
and it could be
a certain species of bacteria.
But unless
you've taken that organism
and added it into your diet
or consumed it,
then it doesn't make it probiotic,
even if it's the same species.
It's not sauerkraut,
sauerkraut is a fermented food
and it has many bacteria in it,
it's beneficial for your health.
But it's not defined as probiotic
because you can't really say that
every single batch
made by every single producer
is the same.
So in order for it
to be a probiotic,
you'd have to define
a specific sauerkraut
and then use the same formulation
each time.
It's not fecal transplant.
Fecal transplant is
the taking off someone's stool
and using those organisms,
essentially as they are,
and transplanting them
into someone else.
And therefore, you can't define
all the organisms
in that fecal transplant.
And you can't be consistent
between each batch
and therefore it's not officially
defined as a probiotic,
even although
it does provide benefits
and it's conferring microorganisms
for health.
It's not multiple strains
never tested on humans.
So some companies unfortunately
produce multiple strains
that they've never shown that
all the strains are needed,
and they've never tested
one versus the other
and looking for additive effects.
So just because
they're multiple strains,
you have to check to see whether
they have been tested in humans.