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1. Introduction
2. "Die Pest" - the Bubonic plague
3. A viewpoint
4. Darwin's principles
5. What do we expect?
6. "Mechanism" versus "function"
7. "Fitness" has many components!
8. Cost of defense (1)
9. Cost of defense (2)
10. A trade-off
11. What kind of costs?
12. Cost of using the defense (1)
13. Encapsulation - a general response
14. Effect of work on immune defense
15. Enforcing the immune response
16. A survival cost of immunity
17. Cost of defense (3)
18. Table: cost of using the defense (1)
19. Table: cost of using the defense (2)
20. Costs of using the defense (2)
21. Worse competitor
22. Table: cost of evolving the defense "machinery"
23. Different interests of the sexes
24. Immune defense and sexual selection studies
25. Specificity (1)
26. Specificity (2)
27. Auto-immunity / self-reactivity
28. Waypoint (1)
29. Strategies: a different view
30. Speed and cost of response (1)
31. Speed and cost of response (2)
32. Limits to removal (1)
33. Limits to removal (2)
34. Waypoint (2)
35. Parasite interference (1)
36. Parasite interference (2)
37. Examples of immune evasions by parasites
38. Strategically robust defenses?
39. Principles of strategic robustness
40. Summary
41. Consequences for medicine
42. (Not) the end...

Topics Covered

• Why immune defense matters
• Asking for evolutionary reasons and constraints
• Using immune defenses is very costly for the individual
• The nature of the costs
• Differences among the sexes
• Specific defenses and their impact
• What would be the best defense
• Parasites are interfering
• The consequences for medicine

Links

Series:

• Evolution and Medicine

Categories:

• Clinical Practice
• Immunology

Therapeutic Areas:

• Immunology & Inflammation
• Infectious Diseases

Talk Citation

Publication History

• Published on October 1, 2007
• Reviewed on August 16, 2020

Financial Disclosures

• Prof. Paul Schmid-Hempel has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.