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Cracking the case of circadian rhythms by Drosophila genetics
A selection of talks on Genetics & Epigenetics
Genetic counseling: preconception, prenatal, perinatal
- Prof. Aubrey Milunsky
- Tufts University School of Medicine, USA
Recent advances in the development of gene delivery technologies
- Dr. Takis Athanasopoulos
- GSK, UK
This presentation will be about biological rhythms, and most of the rhythmic characteristics, that I'll be speaking about have to do with daily rhythms.
Including those, that are exhibited by a fruit fly, one of which is actually indicated over there on the left, Drosophila. The display here of a variety of different kinds of daily rhythms, is not done completely errantly. Because several features, of the outcomes of studying rhythms Drosophila, were better than the investigators intended in a way. Because they spoke to certain components or even several ones, of rhythm control that are operating in many other different kinds of organisms, which is one of the pleasant surprises involving studies of rhythmicity in the fruit fly, Drosophila. I and colleagues began, looking into rhythms Drosophila back in the late 1970s or so. And this refers in a way to the fact that this treatment of rhythms in Drosophila, will have two attributes, one, that it's gonna be largely based on genetics, genetic variance, either mutants or genetic variants that are made by various molecular genetic manipulations. Second, I'm largely going to be treating this subject historically, I will be flashing through many of the pictures here without delving all that deeply into the chronobiological matter in question, but mostly trying to give a survey of how a genetic approach to studying rhythms, notably daily ones, how the genetic approach to these arguably interesting biological problems, came out very well and revealed much in the way about, how rhythms of this sort are regulated. Not only in Drosophila as previewed, but also in other organisms.