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1. Introduction
2. Definition of prion and amyloid
3. Amyloid is usually a pathologic protein form
4. X-ray fiber diffraction
5. Amyloid structure
6. Amyloid fiber growth
7. Human disease-associated amyloids and prions
8. Useful amyloids
9. Prion classification
10. History of scrapie
11. Scrapie in ancient China?
12. Transmissible Spongiform Encephalopathies
13. Yeast and fungal prions
14. Discovery of genes later found to be prions
15. Three genetic criteria to identify a prion
16. [URE3] has the genetic properties of a prion
17. Comparison of prion domains
18. Prion is an infectious protein
19. Vacuolar protease B as a prion
20. Crippled growth of podospora anserina
21. MAP kinases as prions
22. Summery
23. Themes in prions and amyloidoses
24. References

Topics Covered

• Definitions of prions and amyloids
• Genetic criteria for a prion
• Prions of mammals, yeast and filamentous fungi
• Prion domains
• Non-amyloid prions

Links

Series:

• Prions and Amyloids

Categories:

• Biochemistry
• Cell Biology

Therapeutic Areas:

• Neurology

Talk Citation

Publication History

• Published on September 4, 2008

Financial Disclosures

• Prof. Reed Wickner has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.