The influence of host factors on individual susceptibility to tobacco smoke
The pleiotropic genes that control activation (Phase I) and detoxification (Phase II) of potential carcinogens
Effects of the metabolism of environmental compounds on the lipophilic properties of a molecule and the introduction of electronegative moieties within the molecule on carcinogenic potential
Other susceptibility factors related to defects in DNA repair, alterations in tumor suppressor genes and alterations in tumor invasiveness factors
Polymorphisms in genes and the association of this with lung cancer development
The role of inherited polymorphisms of genes involved in xenobiotic metabolism, DNA repair and tumor suppression/invasion (alone and in combination) in lung cancer risk, and modification of this risk by environmental factors such as smoking and diet
Christiani, D. (2007, October 1). Molecular epidemiology of lung cancer [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved February 3, 2023, from https://hstalks.com/bs/80/.
Published on October 1, 2007
Archived on February 25, 2021
Dr. Christiani has served as a paid expert on behalf of victims (plaintiff) cases against tobacco companies.