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Printable Handouts
Navigable Slide Index
- Introduction
- Talk introduction
- Main aim
- Methods
- Experimental protocol
- Steps of cardiac arrest production
- Rats electrocardiogram
- Changes in average heart rate
- Rats electrocorticogram
- Results
- Short-term survival
- Section reacted for horseradish peroxidase
- High magnification of leaking vessels
- Platelets and red cells blocking vessel
- Horseradish peroxidase extravasations
- HRP extravasationts into extracellular space
- Platelets pathology in short-term survival animals
- Platelets pathology in brain ischemia
- C-terminal of amyloid precursor immunoreactivity
- Immunoreactivity for beta-amyloid peptide
- N-terminal of amyloid precursor immunoreactivity
- Long-term survival
- BBB permeability in animals with long-term survival
- BBB changes in white matter of animals
- Large platelet aggregate inside blood vessel
- Two occluded vascular branches
- Occluded vessel bifurcation
- Amyloid precursor protein positive material (1)
- Extra cellular amyloid precursor protein deposits
- Amyloid precursor protein positive material (2)
- Extra cellular amyloid precursor protein deposits
- High magnification of vessel
- Verifection of white matter in vicinity of vessels
- Beta-amyloid peptide immunoreactivity
- Beta-amyloid peptide plaque-like deposits
- Evidence of beta-amyloid peptide circulatory origin
- Experimental procedures - group 1
- Experimental procedures - group 2
- Observations (1)
- Observations (2)
- Observations (3)
- Observations (4)
- Observations (5)
- Scheme of ischemic amyloid plaques development
- Conclusion
- Acknowledgements
- References
Topics Covered
- Ischemic blood-brain barrier involved in Alzheimer's amyloid plaques development and full-blown Alzheimer's disease
- Brain ischemia starts Alzheimer's disease
- Association and risk factors for Alzheimer's disease
- Ischemic mechanisms in Alzheimer's disease in general
Talk Citation
Pluta, R. (2008, March 1). Ischemic blood-brain barrier and Alzheimer's amyloid plaques development [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 5, 2024, from https://doi.org/10.69645/AAYT4390.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Ryszard Pluta has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Ischemic blood-brain barrier and Alzheimer's amyloid plaques development
Published on March 1, 2008
24 min
A selection of talks on Neuroscience
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