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1. Introduction
2. Examples of degradative plasmids (1)
3. Examples of degradative plasmids (2)
4. Examples of degradative plasmids (3)
5. Xylene and toluene degradation by TOL plasmids
6. Degradation pathway genes regulation on pWWO
7. The chloro-catechol ortho-cleavage pathway
8. Catabolic pathways/genes in 2,4-D degradation
9. Chloro-catechol and chloro-hydroxyquinol genes
10. Chemostatic evolution of 2,4,5-T degradative genes
11. Unusual genomic structure of the 2,4,5-T genes
12. Sequence characteristics of the clc element
13. Evolution of s-triazine degradative plasmids
14. Azurin as an "anticapavi" agent
15. Azurin is able to interact with different targets
16. Structural features of azurin and immunoglobulins
17. Secretion of azurin upon exposure to cancer cells
18. Is azurin secreted due to cell lysis?
19. Is azurin secretion energy dependent?
20. Other cellular components released with azurin
21. Sequences in released extrachromosomal DNA
22. Released CpG-rich DNA has anti-tumor activity

Topics Covered

• Examples of degradative plasmids
• Xylene and toluene degradation by TOL plasmids
• The chloro-catechol orthocleavage pathway
• Catabolic pathways/genes in 2,4-D degradation
• Chemostatic evolution of 2,4,5-T degradative genes
• Unusual genomic structure of the 2,4,5-T genes
• Sequence characteristics of the clc element
• Evolution of s-triazine degradative plasmids
• Azurin interaction with different targets
• Structural features of azurin and immunoglobulins
• Secretion of azurin upon exposure to cancer cells
• Sequences in released extrachromosomal DNA
• Released CpG-rich DNA has anti-tumor activity

Links

Series:

• Biology and Significance of Plasmids

Categories:

• Genetics & Epigenetics
• Methods
• Microbiology

Talk Citation

Chakrabarty, A. (2008, January 28). Bacterial extrachromosomal elements: role in chemical detoxification and potential cancer therapy [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 15, 2025, from https://doi.org/10.69645/ONWI6643.
Export Citation (RIS)

Publication History

• Published on January 28, 2008
• Archived on February 25, 2021

Financial Disclosures

• Prof. Ananda Chakrabarty has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.