Chromatin Architecture and the Regulation of
Gene Expression prepared and presented by Jeffrey Hansen,
Professor of Biochemistry and Molecular Biology, Colorado State University.
Hello and welcome to
the presentation on Chromatin Architecture and the Control of Gene Expression.
This talk is organized into six sections.
I begin with a brief overview of Chromatin Architecture and
its relevance to Gene Expression in Eukaryotic organisms.
I then, describe in more detail the many different levels of
chromatin organization found in interphase chromosomes.
As a transition into Gene Expression,
I highlight three Milestone Experiments,
each of which established that transcription in
Eukaryotes is fundamentally dependent on chromatin structure.
This is followed by a large section that focuses on
the Regulation of Gene Expression through Alteration of Chromatin Architecture.
I end by emphasizing the dynamic nature of the genome in vivo,
and by highlighting important future questions in this area.
My overall objective is to further your understanding of chromatin structure,
and its many roles in determining how Eukaryotic genomes are organized and deciphered.