Skip to main content
Search

Pharmacotherapy for obesity: hunger suppressors

Part 2 of 2
Published on February 27, 2025   35 min

Other Talks in the Series: Obesity: Science, Medicine and Society

Please wait while the transcript is being prepared...
0:00
I'm Joe Proietto. I am a professor emeritus at the University of Melbourne. This is Part 2 of the lectures on pharmacotherapy for obesity. I gave my potential conflicts of interest in Part 1.
0:21
The vigorous defense of body weight is the reason why obesity must be treated with hunger-suppressing medications that, in fact, have to be continued even after the patient has lost weight. As you saw from the last lecture, this may need to be lifelong.
0:45
What hunger suppressors do we have? First of all, there are ketones that suppress hunger and these are homemade because ketones are made in the liver. Pharmacological agents you can see listed there; phentermine, liraglutide, naltrexone/bupropion, phentermine and topiramate, and semaglutide 2.4 plus some diabetes medications that have an influence on weight.
1:22
How do ketones suppress hunger? The brain can metabolize ketones. In this paper by Stephanie Amiel and her husband Edwin Gale, they showed that the brain can metabolize ketones.

Quiz available with full talk access. Request Free Trial or Login.

Show
Hide

Pharmacotherapy for obesity: hunger suppressors

Embed in course/own notes