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1. Introduction
2. Diabetes and CVD risk in Framingham cohort
3. Population attributable risk percent effects - men
4. Population attributable risk percent effects - women
5. Natural history of type 2 diabetes
6. Typical levels of insulin sensitivity
7. Assessment of insulin resistance
8. Increased CVD risk factors precede type 2 DM
9. Insulin resistance and atherosclerosis
10. Syndrome X
11. Metabolic traits cluster with hyperinsulinemia
12. Risk variables for a metabolic syndrome
13. Shared risk variables
14. CHD mortality and hyperinsulinemia
15. Diabetes and lipid extremes - men
16. Diabetes and lipid extremes - women
17. Adiposity and vascular inflammation
18. ATP III: the metabolic syndrome
19. ATP III: the metabolic syndrome since 2001
20. WHO: the metabolic syndrome
21. IDF: the metabolic syndrome
22. Age specific prevalence
23. Age-adjusted prevalence by race/ethnicity
24. Prevalence of the metabolic syndrome
25. Prevalence of coronary artery calcification (1)
26. Prevalence of coronary artery calcification (2)
27. Left ventricular mass according to insulin resistance
28. Mean CRP levels and the number of components
29. Metabolic syndrome risk factor sum - men
30. Metabolic syndrome risk factor sum - women
31. Metabolic syndrome outcomes - men
32. Metabolic syndrome outcomes - women
33. Metabolic syndrome factors age adjusted risk
34. Metabolic syndrome clustering
35. Prevalence of metabolic syndrome clustering
36. Metabolic syndrome clustering and relative risk
37. Age-adjusted hazard ratios for MI
38. Age and sex-adjusted hazard ratios
39. Risk for CHD events and new onset diabetes
40. Development of T2DM and CVD
41. Summary

Topics Covered

• The effect of diabetes, obesity and overweight on risks for heart disease
• Framingham Heart Study analyses
• The effects in men and women
• Metabolic studies of new diabetes
• Population studies
• Metabolic risk factor abnormalities generally precede the development of type 2 diabetes mellitus and contribute to the development of diabetes mellitus and accelerated atherosclerosis
• Differences in lipids and triglycerides
• Prevalence of the syndrome rises with age: increased risk of diabetes mellitus, subclinical vascular disease and clinical cardiovascular disease
• Risk for the development of vascular disease
• The European DECODE study
• The AFCAPS study
• Presence of the metabolic syndrome and increased levels of the inflammatory marker CRP may help to identify persons at higher risk of type 2 diabetes or vascular disease

Links

Series:

• Obesity

Categories:

• Clinical Practice

Therapeutic Areas:

• Cardiovascular & Metabolic

Talk Citation

Wilson, P. (2007, October 1). Obesity, diabetes and the cluster of the metabolic syndrome [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 19, 2025, from https://doi.org/10.69645/FWJG2528.
Export Citation (RIS)

Publication History

• Published on October 1, 2007
• Archived on February 25, 2021

Financial Disclosures

• Prof. Peter Wilson has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.