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Multiple endocrine hyperfunction in McCune-Albright syndrome

Published on June 30, 2024   31 min

A selection of talks on Clinical Practice

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0:00
Multiple endocrine hyperfunction in McCune-Albright syndrome. My name is Roberto Lala. I am an Italian medical doctor. I have been head of the pediatric endocrinology unit of Regina Margherita Children's Hospital, Turin. The first patient with McCune-Albright syndrome I met was about three decades ago. I have collected an experience about Italian patients with McCune Albright syndrome. My city is Turin in Italy.
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Patients' selection. When speaking about McCune Albright syndrome, you have to pay attention to the main symptoms which are peripheral precocious puberty, skin cafè-au-lait spots, and fibrous osseous dysplasia. These three symptoms define the syndrome in general, but we will see afterward that the syndrome is heterogeneous in size, symptom, and expression. McCune Albright syndrome contains and can give source to multiple endocrine hyperfunctions. Today, we will speak about those, but we will not forget that there are several isolated endocrine hyperfunctions also. These are gonadal hyperfunctions, pituitary GH-secreting adenomas, pituitary ACTH-secreting adenomas, adrenal adenomas, thyroid nodules.
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Multiple endocrine hyperfunction in McCune-Albright syndrome

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