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0:00
Hello. My name is Kevin Yuen.
I'm a Professor of medicine
and Medical Director at
the Barrow Neurological
Institute in Phoenix, Arizona.
Today my talk to
you is entitled,
Management of Cushing
Syndrome: The tough Questions.
0:18
I'd like to start off
with by giving you
my personal disclaimer
of trying to
understand Cushing's
syndrome since
I was a medical student.
It is pretty common
that people who are
unskilled and unaware of
their own abilities
often in this study
they found that the self
inflated assessments
tends to be quite frequent.
You can see here that when I
first learned about
Cushing's syndrome,
I thought I knew everything.
It turns out that,
in fact, the more I learn,
the more it became more
complicated for me.
At that point in time,
there's a valley of despair
where I'm never going
to understand this.
But eventually, over
time, the more I learned,
it starts to make sense
and eventually it
is a complicated condition,
no question about it.
That's why I'm presenting
this talk to you.
Hopefully, to demystify and
improve the understanding
of this very complicated,
yet interesting and
challenging disease.
1:20
Hypercortisolism can actually
present in many ways.
You can see here in
the figures below that
there is a variety of
presentation in the patient.
It can range from
less severe where
the biochemical
abnormalities for
cortisol secretion
is less severe.
Patients may actually
not experience
much in the way of
clinical symptomatology to
severe hypercortisolism
where cortisol levels are
generally tend to
be very high and
patients can present with
the classic features
of moon phase,
buffalo hump, striae as you
can see in the figure below.
