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0:00
Hello, my name is Suma Uday.
I am a consultant
endocrinologist at
Birmingham Children's Hospital,
in Birmingham, in the UK.
I am also an Honorary
Associate Clinical Professor
at the University of Birmingham.
The topic of my
discussion today is
the clinical spectrum
of hypophosphataemia,
that is low phosphate
in children.
I would like to sincerely thank
Henry Stewart Talks for
inviting me to
deliver this lecture.
0:31
These are my disclosures:
I would like to specifically
mention that I am
an expert panel member on
the International
Hypophospotemia Network,
which is a Kyowa
Kirin information hub
for healthcare professionals.
Some of the educational
material that I will be
using today were developed for
the purpose of this network.
0:51
Over the next 30 minutes or so,
I will detail the spectrum of
conditions caused by
hypophosphataemia.
As the title suggests,
the scope of this talk is to
provide an overview of
the various conditions
only and not to discuss
the diagnosis and management
of each of these in depth.
I will start with a brief
overview of the role
of phosphate in humans and
phosphate homeostasis.
I will detail the
clinical features
of low phosphate and provide
a logistic approach
to investigating
children presenting
with hypophosphataemia,
which focuses on
the assessment of
pathophysiologic
mechanisms that lead
to low serum phosphate
concentrations.
Through some case studies,
I will elaborate on these
specific conditions.
Phosphate is one of
