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Printable Handouts
Navigable Slide Index
- Introduction
- Outline
- What is evolutionary developmental biology?
- Definition of evolutionary developmental biology
- Example: tetrapod limb
- EVO-DEVO study
- Case study: digit reduction in mammals
- Fgf8 and Shh (1)
- Fgf8 and Shh (2)
- Post condensation reduction
- Multiple developmental changes contribute to digit reduction
- Case study: digit reduction in skinks
- Digit reduction in horses and other amniotes
- Limb reduction: construction and deconstruction
- Modern synthesis
- Why evolutionary developmental biology?
- Unique insights from evo-devo/devo-evo
- Generation of variation: phenotypic integration and modularity (1)
- Generation of variation: phenotypic integration and modularity (2)
- Generation of variation case study: avian skull
- Rate and variance are heterogenous
- Module integration and evolution reflects developmental origin
- Constraints are important modulators
- Phenotypic integration and modularity: fly in a test tube
- Case studies: origin of morphological innovation
- Origin of morphological innovation: beetle horns
- Wing genes are required for prothoracic horn formation
- Beetle horns: predictions
- Exploring novel structures: beetle horns
- Beetle horns: which predicition?
- Wing-related genes (1)
- Wing-related genes (2)
- Novel structures in other insects
- Origin of morphological innovation: take home
- Future of evolution developmental biology
- Thank you for listening
Topics Covered
- Evolutionary developmental biology
- Evolution of the tetrapod limb
- Digit reduction in mammals
- Modern synthesis
- Phenotypic integration and modularity
- The generation of variation
- Origin of morphological innovation
- Novel structures: beetle horns
Talk Citation
Sears, K. (2023, January 31). Evolutionary developmental biology [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 22, 2024, from https://doi.org/10.69645/SLHM3581.Export Citation (RIS)
Publication History
Financial Disclosures
- Dr. Karen Sears has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Other Talks in the Series: Introduction to Evolutionary Biology
Transcript
Please wait while the transcript is being prepared...
0:00
Hello, my name is Karen Sears.
I'm a professor at UCLA.
In this talk I'm going to
present an introduction to
the field of evolutionary
developmental biology.
0:13
I will first provide
an overview of
the general aims of the field
of evolutionary
developmental biology.
Then I will talk a bit about
why evolutionary
developmental biology is
important to a
complete understanding
of the evolutionary
history of life.
Next step, we'll go
through two case studies
that touch on two
topics that I feel are
really at the center of much of
evolutionary developmental
biological research.
These are the generation of
variation and the origin of
morphological innovation.
Last, I will briefly
touch on the future
of the field of evolutionary
developmental biology.
0:52
First, things first.
To provide a foundation
for the rest of this talk,
I'm going to spend a few
minutes talking about
the general aims and focus
of the field of evolutionary
developmental biology.
Broadly defined as spoiled
by the name of the field,
evolutionary developmental
biology bridges the fields
of developmental biology
and evolutionary biology.
When I speak about
developmental biology,
I am referring to the study of
the processes by which
animals and plants
grow and develop.
For example in this
image on the left,
it shows the early
development of
the limbs of mammals from
their initial outgrowths
from the body wall to when
they start to resemble
a form that looks more like
what they will look
like in the adults.
When I speak about
evolutionary biology,
I'm referring to the study of
the processes and patterns
of biological evolution,
especially in relation to
the diversity of organisms and
how they change over time.
For example, in the
image on the right,
I show the
morphological diversity
displayed by the limbs
of adult mammals.
Note when I say the
word morphology,
I'm referring to an
organism's form.