• Defining Retroviruses
• 38 min
  1. An introduction to retroviruses: replication strategy and genetics

  • Dr. Jonathan Stoye
• 45 min
  2. Bovine leukemia virus

  • Prof. Arsene Burny
  • Dr. Lucas Willems
• The First Human Retroviruses
• 65 min
  3. The discovery of human retroviruses and how they cause disease

  • Prof. Robert Gallo
• HIV - Peculiarities of its Genome
• 11 min
  4. HIV: peculiarities of its genome

  • Dr. George Pavlakis
• HIV Transmission, Epidemiology and Public Health/Prevention Issues
• 42 min
  5. HIV/AIDS epidemiology, transmission, and risk factors

  • Prof. William Blattner
• 55 min
  6. HIV prevention and public health issues: a global perspective

  • Prof. Sten H. Vermund
• How HIV causes AIDS
• 35 min
  7. How HIV causes disease 1: identification and characterization of HIV

  • Prof. Bruce Walker
• 43 min
  8. How HIV causes disease 2: immune responses to HIV infection

  • Prof. Bruce Walker
• HIV Therapy - Now and the Future
• 34 min
  9. HIV therapy: taking advantage of progress

  • Prof. Paul Volberding
• 39 min
  10. HIV cure: harnessing innate and adaptive strategies

  • Prof. Luis Montaner
• Archived Lectures *These may not cover the latest advances in the field
• 36 min
  11. The first human retroviruses: the human T lymphotropic viruses (HTLVs)

  • Prof. William Hall
• 59 min
  12. HIV preventive vaccines

  • Prof. Andrew McMichael
• 31 min
  13. HIV/AIDS in the developing world: what can we do?

  • Dr. Joseph O'Neill
• 54 min
  14. Human T-cell leukemia virus type 1 (HTLV-1) and adult T-cell leukemia: insights into cellular transformation

  • Prof. Kuan-Teh Jeang
• 41 min
  15. Antiretroviral therapy 2007, new concepts and lessons learned

  • Prof. Robert Redfield
• 29 min
  16. What to do in therapy in the face of HIV drug resistance?

  • Prof. Mark Wainberg
• 42 min
  17. Viral reservoirs, latency and mechanisms of HIV persistence

  • Prof. Robert Siliciano
• 28 min
  18. HIV preintegration complexes

  • Prof. Lee Ratner
• 30 min
  19. The discovery of ATL field expansion in 40 yrs

  • Prof. Junji Yodoi

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. Organization of the HIV-1 genome
3. HIV-1 mRNAs
4. Env and HIV-1 entry
5. Tat and Rev - essential RNA binding proteins
6. HIV-1 promoter
7. HIV-1 mRNA expression (1)
8. HIV-1 mRNA expression (2)
9. The Rev/CRM1 mRNA export pathway
10. Specialized export mechanisms of retroviruses
11. HIV-1 regulatory and accessory proteins
12. HIV-1 proteins as molecular adaptors
13. The importance of CD4 regulation
14. HIV research has benefited many fields
15. HIV-1 genome

Topics Covered

• Molecular organization of HIV
• HIV-1 mRNAs
• Env and HIV-1 entry
• Tat and Rev are essential RNA binding HIV-1 proteins
• HIV-1 promoter
• HIV-1 mRNA expression
• Retroviruses and Env-containing LTR-retroelements depend on specialized mRNA export mechanisms to express their full-length mRNA
• The Rev/CRM1 mRNA export pathway
• HIV-1 regulatory and accessory proteins
• HIV-1 proteins as molecular adaptors
• The importance Of CD4 regulation
• HIV-1 genome

Links

Series:

• Retroviruses

Categories:

• Genetics & Epigenetics
• Immunology
• Microbiology

Therapeutic Areas:

• Infectious Diseases

Talk Citation

Publication History

• Published on October 1, 2007

Financial Disclosures

• Dr. George Pavlakis has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.