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Navigable Slide Index

1. Introduction
2. Hormones and breast cancer
3. Cellular origin of breast cancer
4. Stages in cancer development
5. Different types/stages of breast cancers
6. Established hormonal risk and protective factors
7. Hormones and the etiology of breast cancer
8. Steroid hormone receptor isoforms
9. Steroid hormone mechanism of action
10. Structural basis of DNA binding
11. Additional estrogen/estrogen receptor pathways
12. ER effectors
13. ER-alpha and estrogen in breast tumors
14. Hormonal issues in breast cancer treatment
15. Hormone replacement therapy
16. Women's health initiative study
17. Environmental "estrogens"
18. Estrogen synthesis and metabolism
19. Synthetic ER ligands and cellular responses
20. Tamoxifen therapy for breast cancer
21. Prevention of breast cancer?
22. Alternative hormonal approaches
23. Additional hormones affecting breast cancer
24. Summary and outstanding research questions

Topics Covered

• Development and types of breast cancers
• Molecular and cellular aspects of hormone action on breast cells
• Natural and synthetic estrogens
• Basis for endocrine therapies
• Alternative/emerging therapeutic approaches
• Strategies for breast cancer prevention

Links

Series:

• The World of Hormones

Categories:

• Biochemistry
• Cancer
• Reproduction & Development

Therapeutic Areas:

• Oncology

Talk Citation

Welsh, J. (2007, December 1). Steroid hormones and their receptors in breast cancer [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 15, 2025, from https://doi.org/10.69645/PBHC2027.
Export Citation (RIS)

Publication History

• Published on December 1, 2007
• Archived on August 13, 2020

Financial Disclosures

• Prof. JoEllen Welsh has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.