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Topics Covered
- Measuring viral RNA in sewage water: methods and insights
- Reliability of measuring SARS-CoV-2 RNA in sludge
- Estimation of time lag between appearance of viral RNA in sewage water and start of outbreak
- Implications of introducing public health measures
- Increased efficiency of public health responses using viral RNA in sewage water
Biography
Jordan Peccia is the Thomas E. Golden Jr. Professor of environmental engineering at Yale University. His research mixes genetics with engineering to study childhood exposure to bacteria, fungi and viruses in buildings. Peccia is a member of Connecticut Academy of Science and Engineering and associate editor for the journal Indoor Air. He earned his PhD in environmental engineering from the University of Colorado.
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Talk Citation
Peccia, J. (2020, August 17). Predicting COVID-19 outbreaks by measuring SARS-CoV-2 RNA in sewage sludge [Audio file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 26, 2024, from https://hstalks.com/bs/4373/.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Jordan Peccia has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
A selection of talks on Respiratory Diseases
Transcript
Please wait while the transcript is being prepared...
0:00
Interviewer: Professor Jordan Peccia,
thank you very much for
taking the time to do this interview
with us today to discuss novel and
ingenious ways of predicting
future COVID-19 outbreaks, and
also the means of anticipating their
resulting public health responses.
Let me start by asking about
your recently published work,
which showed the possibility of
testing local sewage water for
levels of SARS-CoV-2 RNA as
markers of impending outbreaks.
Can you explain a little bit about how
this is measured and what you have found?
Prof. Peccia: We're able to measure
the virus that causes COVID-19,
which is called SARS-CoV-2 in sewage,
in a similar manner to the way that
the virus is measured if you go in to take
an individual test to see if you're
infected or not with the virus.
The name of the test is called a Reverse
Transcriptase Quantitative PCR Assay.
What that does is it detects the very
specific parts of the viral RNA in
the SARS-CoV-2 virus.
We're not only able to detect
that virus specifically, but
we're able to quantify the concentration
of the virus in the sewage.
Now we aren't able to quantify whether
it's alive or whether it's dead,
just whether the DNA, or
rather the RNA in this case, is there.
When we did so in the sewage sludge in
Southern Connecticut in the city I live
in which is called New Haven, we were
able to determine that as the cases rose,
we were also able to see that
the viral concentration rose.
Now that we're on the other side of the
outbreak and the cases start to decline,
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