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1. Introduction to biochemistry
- Prof. Gerald W. Feigenson
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2. Amino acids and peptides
- Prof. Gerald W. Feigenson
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3. Protein structure principles
- Prof. Gerald W. Feigenson
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4. Observed protein structures
- Prof. Gerald W. Feigenson
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5. Protein folds and IV structure
- Prof. Gerald W. Feigenson
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6. Protein stability and folding
- Prof. Gerald W. Feigenson
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7. Haemoglobin structure and stability
- Prof. Gerald W. Feigenson
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8. Enzyme specificity and catalysis
- Prof. Gerald W. Feigenson
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9. Enzyme kinetics (Michaelis-Menten)
- Prof. Gerald W. Feigenson
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10. Enzyme inhibition; chymotrypsin
- Prof. Gerald W. Feigenson
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11. Enzyme regulation and coenzymes
- Prof. Gerald W. Feigenson
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12. Lipids, biomembranes and membrane proteins
- Prof. Gerald W. Feigenson
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13. Structure and function of carbohydrates
- Prof. Gerald W. Feigenson
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14. Metabolism principles
- Prof. Gerald W. Feigenson
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15. Glycolysis - energy and useful cell chemicals
- Prof. Gerald W. Feigenson
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16. Glycolysis control
- Prof. Gerald W. Feigenson
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17. Metabolism of pyruvate and fat
- Prof. Gerald W. Feigenson
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18. Urea cycle; oxidative phosphorylation 1
- Prof. Gerald W. Feigenson
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19. Urea cycle; oxidative phosphorylation 2
- Prof. Gerald W. Feigenson
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20. Light-driven reactions in photosynthesis
- Prof. Gerald W. Feigenson
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21. Gluconeogenesis and the Calvin cycle
- Prof. Gerald W. Feigenson
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22. Synthesis of lipids and N-containing molecules 1
- Prof. Gerald W. Feigenson
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23. Synthesis of lipids and N-containing molecules 2
- Prof. Gerald W. Feigenson
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24. Hormone mechanisms
- Prof. Gerald W. Feigenson
Printable Handouts
Navigable Slide Index
- Introduction
- Lecture outline
- Limited variety of compounds & reactions in life
- Biomembranes: General properties
- 3 key types of lipid bilayer phases
- Coexisting membrane phases
- Fatty acyl chains found in biomembranes
- Structure of some bilayer-forming lipids
- Phospholipases
- Proteins in biomembranes & association types
- A "real" membrane: red blood cell membrane
- What do real cell membranes actually look like?
- A look at some membrane proteins
- Membrane fusion
- Lecture summary
Topics Covered
- Properties of biomembranes
- Types of lipid bilayer phases
- Types of fatty acyl chains
- Phospholipases
- Types of membrane association
- Membrane fusion
Talk Citation
Feigenson, G.W. (2022, November 27). Lipids, biomembranes and membrane proteins [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved November 10, 2024, from https://doi.org/10.69645/LKCA2724.Export Citation (RIS)
Publication History
Financial Disclosures
- Gerald Feigenson has no commercial/financial relationships to disclose.
Request access to the Principles of Biochemistry lecture series, an extensive introductory to the field of biochemistry. An HSTalks representative will contact you with more information about this series and getting unrestricted access to it.
A selection of talks on Biochemistry
Transcript
Please wait while the transcript is being prepared...
0:00
Greetings. Welcome
to this Principles
of Biochemistry lecture series.
I am Jerry Feigenson.
I am a professor in
the Department of
Molecular Biology &
Genetics at Cornell
University in the USA.
In the 11th lecture,
you saw that many proteins need
non-amino acid
components, such as
small molecules and
ions in order to
perform the wide range of
biochemical catalysis.
Then, we examined how
enzymes can be controlled,
either by controlling
their concentration
or by controlling their
catalytic activity.
We looked at two examples of
activity control in detail,
allosteric control of
ATCase and peptide bond
cleavage to create
active chymotrypsin.
In this 12th lecture,
0:56
you will learn that
biomembrane components
are mainly 2-chain
phospholipids,
sterols like cholesterol,
and membrane proteins.
You will see that
biomembranes can
have interesting
phase behaviors and
I will introduce you to
phospholipase enzymes that
catalyze lipid
breakdown, creating
different chemicals
used by the cell.
You will see that
proteins are anchored to
the membrane in six
particular ways.
Finally, you will see
that membrane fusion occurs
and is under control.