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Printable Handouts
Navigable Slide Index
- Introduction
- Ca2+ signal generation
- Ca2+ release from internal stores
- The discovery of intracellular Ca2+ release
- Effect of ACh and adrenaline on Ca2+ release
- Effect of intracellular Ca2+ injection
- Ca2+ - mediated agonist-elicited channel opening
- Techniques used in studying Ca2+ signaling
- ACh elicits repetitive Ca2+ spikes through IP3Rs
- Ach causes repetitive release of Ca2+ from ER
- ACh elicits IP3 formation, IP3 releases Ca2+
- ER penetrates into granular pole, where IP3Rs are
- cADPR and NAADP also elicit local Ca2+ spikes
- CCK action is dependent on NAADP receptors
- Local/global Ca2+ oscillations in intact pancreas
- Globalisation of Ca2+ signal
- Summary of part 1
- Ca2+-dependent release of NO
- Ca2+ release by supramaximal ACh stimulation
- The ER is a functional Ca2+ tunnel (1)
- The ER is a functional Ca2+ tunnel (2)
- The mitochondrial Ca2+ buffer barrier
- The secretory granules - another Ca2+ store
- Ca2+ in ER and non-ER stores
- Ca2+ release from granules
- Ca2+ signal generation in the apical granular pole
- Summary of Ca2+ signaling events
Topics Covered
- Calcium release from intracellular stores as opposed to Calcium entry from the external solution
- The pioneers of Calcium signaling
- Patch clamp recording combined with optical Calcium measurements
- Calcium measurements in various organelles
- Different Calcium releasing messengers
- Calcium-mediated NO release
- Calcium tunnels
- Stimulusmetabolism coupling
- Calcium release from the endoplasmic reticulum and from acid stores
- Local and global Calcium signaling also in the intact tissue
Talk Citation
Petersen, O. (2007, October 1). Coordinated Ca2+ release from intracellular Ca2+ stores [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 7, 2024, from https://doi.org/10.69645/BBTY2653.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Ole Petersen has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.