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Printable Handouts
Navigable Slide Index
- Introduction
- Life expectancies in the UK (1841-2017)
- The human genome
- Cost to sequence a human genome (USD)
- Additional genome projects
- Genome editing: CRISPR
- Changes in US corn yield
- Species relatedness
- Pellegra: inherited but not genetic
- Early attempts to explain inheritance
- Gregor Mendel
- Mendel's peas
- Mendel's first experiment
- Mendel's interpretation of his experiment (1)
- Mendel's interpretation of his experiment (2)
- The first human disease pedigree
- Huntington's disease
- Cystic fibrosis: a recessive disease
- Pedigree for cystic fibrosis
- The characters used by Mendel
- Mendel's second 'dihybrid' experiment
- Explaining Mendel's dihybrid cross (1)
- Explaining Mendel's dihybrid cross (2)
- DNA fingerprinting
- Dwarf rice
- The flu virus
- Spanish flu virus sequenced
- Flu viruses are recombinants
- Summary
Topics Covered
- The human genome
- Genome editing
- Why genetics is important today
- Gregor Mendel’s pea experiments and his first law
- Applications of Mendel’s first law in the context of dominant and recessive diseases in humans
- Gregor Mendel’s dihybrid experiments and his second Law
- DNA fingerprinting
- Applications of Mendel’s second law
Talk Citation
Bellamy, L. (2019, March 31). A brief introduction to genetics [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 14, 2019, from https://hstalks.com/bs/3910/.Publication History
Financial Disclosures
- Dr. Lawrence Bellamy has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
A brief introduction to genetics
Published on March 31, 2019
52 min
Other Talks in the Category: Genetics & Epigenetics
Transcript
0:00
Hello, everybody. My name is Dr. Lawrence Bellamy,
and I'm a senior teaching fellow at the University College London in the UK.
I'm going to be giving you a brief introduction to genetics.
0:15
I would like to begin with a graph.
This graph is a reason to be optimistic;
it shows how life expectancies in the UK
have changed over the past 150 years.
Were I giving this lecture 500 years ago in say,
the time of William Shakespeare, two out of
three individuals will be dead by the age of 21.
The reason why life expectancies were so low is that people
were dying from what was called "The enemy outside."
They were dying from infections such as cholera or tuberculosis;
they were dying from things such as famine,
the cold, or even war.
But, today we've kind of controlled this enemy outside,
but there is some bad news you all have to die, eventually.
But, today we die from things that referred to as the enemy within.
Today, we're dying from diseases such as diabetes, cancers,
dementias, all of which, unquestionably, have a genetic component.
That's not to say maintaining health isn't important,
eating healthily and doing exercise,
is important and how your genes interact with
the environment that they're in is another lecture itself.
But, our genes are certainly determining our health today.