Hello everyone, my name is Lili Chan and
I'm currently faculty at the Icahn School
of Medicine at Mount Sinai.
I'm glad you have chosen to learn more
about oxygen saturation in hemodialysis
I think it is interesting that while
we routinely measure blood pressure and
heart rate during hemodialysis, we neglect
the other vital sign of oxygen saturation.
That leads us to our topic of
intradialytic oxygen supplementation,
what does it mean and
should we care about it?
The outline of today's talk will be to
first review what oxygen saturation is and
what we currently know about
hypoxemia in hemodialysis patients,
then we will discuss specifically
Next we will review what we know about
intradialytic central venous oxygen
saturation, and we will finish with
a discussion on what has been done and
what we can do for
abnormal oxygen saturation levels.
Let's start with what
oxygen saturation is and
what we know about hypoxemia
in hemodialysis patients.
Oxygen saturation is the fraction of
hemoglobin with oxygen bound to it over
the total hemoglobin in blood.
As displayed in the graph,
normal oxygen saturation levels
are more than 93% in humans.
There are many different ways that
oxygen saturation can be measured,
displayed here are two of
the most common methods.
On the left is a person obtaining
an arterial blood sample where oxygen
saturation levels can
be directly measured.
On the right is a commercially available
pulse oximeter which measures oxygen
Pulse oximeters measure oxygen saturation
by detecting the differences in absorption
of red and infrared lights between
oxygenated and deoxygenated hemoglobin.