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Printable Handouts
Navigable Slide Index
- Introduction
- Outline
- Diarrhea is a health problem worldwide
- Viruses causing diarrhea in human
- Rotavirus (RV)
- Epidemiology
- Rotavirus pathogenesis
- Rotaviruses infect mature enterocytes
- RV-gnotiobiotic piglets
- Rotavirus infection in calves
- Effects of Rotavirus infection
- Rotavirus genes and proteins
- Rotavirus replication
- Rotavirus life cycle
- Unique particle assembly process
- NSP4: an intracellular receptor and enterotoxin
- NSP4-inoculated mouse
- Intestine of NSP4-inoculated mouse
- Properties of Rotavirus enterotoxin
- How does the Rotavirus enterotoxin NSP4 act?
- Effects of RV infection of polarized epithelial cells
- How does Rotavirus cause diarrhea - summary
- New unexpected information about RV replication
- Treatment and vaccines
- A child with RV infection
- Oral rehydration therapy
- A child after rehydration therapy
- Current status of RV vaccines
- Rotavirus - conclusions
- Norwalk virus (NV)
- Norovirus gastroenteritis
- Norovirus background
- Norovirus pathogenesis
- Clinical responses of two adult volunteers given NV
- 1970s NV studies
- Challenges studying Norwalk virus (NV)
- Virus-like particles (VLPs)
- Norwalk VLPs hemagglutinate red blood cells
- What is the H antigen?
- FUT2 genotype versus NV challenge outcome
- Is host susceptibility similar for all noroviruses?
- Summary: Noroviruses
- Remained questions
Topics Covered
- Viruses causing diarrhea
- Epidemiology
- Rotavirus pathogenesis
- Rotavirus infection in calves
- Rotavirus genes and proteins
- Rotavirus replication
- NSP4
- Properties of rotavirus enterotoxin
- Treatment and vaccines
- Norovirus
- Norovirus pathogenesis
- Challenges studying Norwalk virus
Links
Series:
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Talk Citation
Estes, M. (2007, October 1). Gastroenteritis viruses [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 18, 2025, from https://doi.org/10.69645/IQFQ7727.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Mary Estes has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.