• General Virology
• 46 min
  1. Principles of virology

  • Prof. Vincent Racaniello
• 36 min
  2. The type I interferon system and viruses

  • Dr. Adolfo Garcia-Sastre
• 45 min
  3. Immune responses to viruses

  • Prof. Paul Klenerman
• Emerging Pathogens
• 29 min
  4. Emerging or newly discovered viral causes of acute lower respiratory tract infections worldwide

  • Dr. Marietjie Venter
  • Mrs. Orienka Hellferscee
• 37 min
  5. Emerging respiratory viruses - discoveries between 2001 and 2005

  • Prof. Ron Fouchier
• 28 min
  6. Usage of vaccines and therapeutics in public health emergencies 1

  • Prof. Gary Kobinger
• 39 min
  7. Usage of vaccines and therapeutics in public health emergencies 2

  • Prof. Gary Kobinger
• 50 min
  8. Influenza virus pandemics: past and future

  • Prof. Peter Palese
• 63 min
  9. SARS-CoV and other emerging coronaviruses

  • Prof. Ralph Baric
• 36 min
  10. Dengue, Zika and Chickungunya viruses

  • Prof. Ana Fernandez-Sesma
• 43 min
  11. Paramyxoviruses: biology & pathogenesis

  • Prof. Benhur Lee
• 36 min
  12. Antiviral drugs (non-HIV)

  • Prof. Megan Shaw
• 41 min
  13. Biodefense challenges

  • Dr. David Franz
• Important Pathogens and their Diseases
• 38 min
  14. Natural history and pathogenesis of herpes virus infections

  • Prof. Richard Whitley
• 40 min
  15. Cytomegalovirus biology

  • Prof. Domenico Tortorella
• 46 min
  16. Hepatitis C virus: discovery, cure and protection

  • Dr. Matthew Evans
• 32 min
  17. Fundamentals of HIV biology

  • Prof. Viviana Simon
• 44 min
  18. Measles

  • Prof. Diane E. Griffin
• 42 min
  19. Monkeypox virus, vaccines, and therapeutics

  • Prof. Rachel Roper
• New Frontiers
• 45 min
  20. HPV vaccines to prevent cervical cancer and other HPV-associated diseases

  • Dr. John Schiller
• 55 min
  21. Prevention of Varicella and Zoster by vaccination: Now you see it, now you don't

  • Prof. Anne Gershon
• 30 min
  22. Viruses as anticancer weapons

  • Prof. Roberto Cattaneo
• 48 min
  23. Novel approaches to diagnosis of viral infections

  • Prof. W. Ian Lipkin
• 36 min
  24. The Global Virus Network: collaboration to address pandemic and regional threats

  • Prof. Sten H. Vermund
• 31 min
  25. Elite controllers of HIV: from discovery to future therapies

  • Prof. Bruce Walker
• Archived Lectures *These may not cover the latest advances in the field
• 43 min
  26. Principles of virology I

  • Prof. Richard Condit
• 43 min
  27. Principles of virology II

  • Prof. Richard Condit
• 36 min
  28. Complex DNA viruses: herpes virus

  • Dr. John Blaho
• 38 min
  29. Adeno-associated viruses (AAV)

  • Prof. Kenneth Berns
• 60 min
  30. Poxviruses: smallpox (variola), vaccinia and monkeypox

  • Prof. Paula Traktman
• 26 min
  31. Can HPV testing be the sole primary cervical screening modality?

  • Prof. Jack Cuzick
• 29 min
  32. From viruses to oncolytics

  • Prof. Roberto Cattaneo
• 38 min
  33. Non HIV antivirals

  • Prof. Mary Klotman
• 42 min
  34. Gastroenteritis viruses

  • Prof. Mary Estes
• 46 min
  35. Biodefense challenges

  • Dr. Connie Schmaljohn
• 32 min
  36. Papillomaviruses and HPV vaccination to prevent cervical cancer and other HPV-associated diseases

  • Dr. Douglas Lowy
• 49 min
  37. The past, present and future of vaccination

  • Prof. Stanley Plotkin
• 41 min
  38. Filoviruses

  • Dr. Christopher Basler
• 41 min
  39. Bunyaviruses

  • Prof. Richard Elliott
• 41 min
  40. The immunobiology of HIV

  • Prof. Norman Letvin
• 59 min
  41. Hepatitis C and HCV

  • Prof. Stanley Lemon

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. Lecture objective
3. Encephalitic brain
4. Herpesviridae
5. Subfamilies of Herpesviridae
6. Human herpesviruses
7. Herpesvirus associated disease in humans
8. Herpesvirus pathogenesis
9. HSV-1 pathogenesis
10. Clinical manifestations of HSV-1 infection
11. Primary HSV-1 infection
12. Recurrent HSV-1 infection
13. Ocular HSV-1 infection
14. Disseminated HSV-1 infection
15. HSV-2 pathogenesis
16. HSV-2 infection
17. Herpes whitlow
18. HSV-2 infection of the newborn
19. Model for primary and recurrent HSV-1 infection
20. HSV replication
21. Electron micrographs of HSV replication stages
22. HSV gene expression
23. Expression of immediate early genes
24. Sequence of transcription events
25. Final stages of HSV replication cycle
26. HSV replication - summary
27. VZV pathogenesis
28. Varicella (chicken pox)
29. Primary chicken pox infection
30. The crops
31. Neonatal Varicella
32. Zoster (shingles)
33. Zoster (shingles) lesions
34. Herpes Zoster ophthalmicus (shingles)
35. Disseminated VZV
36. CMI controls VZV
37. VZV vaccine
38. HSV/VZV diagnostics
39. HSV cytopathic effect (CPE)
40. Tzanck test
41. Acyclovir
42. Acyclovir molecule
43. Famciclovir
44. Valacyclovir
45. Valtrex vs. Acyclovir
46. HSV response to oral Acyclovir
47. HSV response to i.v. Acyclovir
48. HSV response to i.v. Vidarabine
49. HSV response to i.v. Foscarnet
50. Conclusion

Topics Covered

• Introduction to human herpes viruses
• Common characteristics
• Herpes virus replication
• Attachment/penetration
• Gene expression/cascade regulation
• DNA synthesis
• Assembly and packaging
• Viral budding
• Evasion of the immune response
• Herpes virus pathogenesis
• Cytopathic effect
• HSV and VZV diagnosis, treatment and control

Links

Series:

• Viruses and Viral Diseases

Categories:

• Clinical Practice
• Microbiology

Therapeutic Areas:

• Infectious Diseases

Talk Citation

Publication History

• Published on October 1, 2007
• Archived on September 14, 2017

Financial Disclosures

• Dr. John Blaho has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.