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1. Introduction
2. Lecture objective
3. Encephalitic brain
4. Herpesviridae
5. Subfamilies of Herpesviridae
6. Human herpesviruses
7. Herpesvirus associated disease in humans
8. Herpesvirus pathogenesis
9. HSV-1 pathogenesis
10. Clinical manifestations of HSV-1 infection
11. Primary HSV-1 infection
12. Recurrent HSV-1 infection
13. Ocular HSV-1 infection
14. Disseminated HSV-1 infection
15. HSV-2 pathogenesis
16. HSV-2 infection
17. Herpes whitlow
18. HSV-2 infection of the newborn
19. Model for primary and recurrent HSV-1 infection
20. HSV replication
21. Electron micrographs of HSV replication stages
22. HSV gene expression
23. Expression of immediate early genes
24. Sequence of transcription events
25. Final stages of HSV replication cycle
26. HSV replication - summary
27. VZV pathogenesis
28. Varicella (chicken pox)
29. Primary chicken pox infection
30. The crops
31. Neonatal Varicella
32. Zoster (shingles)
33. Zoster (shingles) lesions
34. Herpes Zoster ophthalmicus (shingles)
35. Disseminated VZV
36. CMI controls VZV
37. VZV vaccine
38. HSV/VZV diagnostics
39. HSV cytopathic effect (CPE)
40. Tzanck test
41. Acyclovir
42. Acyclovir molecule
43. Famciclovir
44. Valacyclovir
45. Valtrex vs. Acyclovir
46. HSV response to oral Acyclovir
47. HSV response to i.v. Acyclovir
48. HSV response to i.v. Vidarabine
49. HSV response to i.v. Foscarnet
50. Conclusion

Topics Covered

• Introduction to human herpes viruses
• Common characteristics
• Herpes virus replication
• Attachment/penetration
• Gene expression/cascade regulation
• DNA synthesis
• Assembly and packaging
• Viral budding
• Evasion of the immune response
• Herpes virus pathogenesis
• Cytopathic effect
• HSV and VZV diagnosis, treatment and control

Links

Series:

• Viruses and Viral Diseases

Categories:

• Clinical Practice
• Microbiology

Therapeutic Areas:

• Infectious Diseases

Talk Citation

Publication History

• Published on October 1, 2007
• Archived on September 14, 2017

Financial Disclosures

• Dr. John Blaho has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.