We noted you are experiencing viewing problems
-
Check with your IT department that JWPlatform, JWPlayer and Amazon AWS & CloudFront are not being blocked by your network. The relevant domains are *.jwplatform.com, *.jwpsrv.com, *.jwpcdn.com, jwpltx.com, jwpsrv.a.ssl.fastly.net, *.amazonaws.com and *.cloudfront.net. The relevant ports are 80 and 443.
-
Check the following talk links to see which ones work correctly:
Auto Mode
HTTP Progressive Download Send us your results from the above test links at access@hstalks.com and we will contact you with further advice on troubleshooting your viewing problems. -
No luck yet? More tips for troubleshooting viewing issues
-
Contact HST Support access@hstalks.com
-
Please review our troubleshooting guide for tips and advice on resolving your viewing problems.
-
For additional help, please don't hesitate to contact HST support access@hstalks.com
We hope you have enjoyed this limited-length demo
This is a limited length demo talk; you may
login or
review methods of
obtaining more access.
- General Virology
-
1. Principles of virology
- Prof. Vincent Racaniello
-
2. The type I interferon system and viruses
- Dr. Adolfo Garcia-Sastre
-
3. Immune responses to viruses
- Prof. Paul Klenerman
- Emerging Pathogens
-
4. Emerging or newly discovered viral causes of acute lower respiratory tract infections worldwide
- Dr. Marietjie Venter
- Mrs. Orienka Hellferscee
-
5. Emerging respiratory viruses - discoveries between 2001 and 2005
- Prof. Ron Fouchier
-
6. Usage of vaccines and therapeutics in public health emergencies 1
- Prof. Gary Kobinger
-
7. Usage of vaccines and therapeutics in public health emergencies 2
- Prof. Gary Kobinger
-
8. Influenza virus pandemics: past and future
- Prof. Peter Palese
-
9. SARS-CoV and other emerging coronaviruses
- Prof. Ralph Baric
-
10. Dengue, Zika and Chickungunya viruses
- Prof. Ana Fernandez-Sesma
-
11. Paramyxoviruses: biology & pathogenesis
- Prof. Benhur Lee
-
12. Antiviral drugs (non-HIV)
- Prof. Megan Shaw
-
13. Biodefense challenges
- Dr. David Franz
- Important Pathogens and their Diseases
-
14. Natural history and pathogenesis of herpes virus infections
- Prof. Richard Whitley
-
15. Cytomegalovirus biology
- Prof. Domenico Tortorella
-
16. Hepatitis C virus: discovery, cure and protection
- Dr. Matthew Evans
-
17. Fundamentals of HIV biology
- Prof. Viviana Simon
-
18. Measles
- Prof. Diane E. Griffin
-
19. Monkeypox virus, vaccines, and therapeutics
- Prof. Rachel Roper
- New Frontiers
-
22. Viruses as anticancer weapons
- Prof. Roberto Cattaneo
-
23. Novel approaches to diagnosis of viral infections
- Prof. W. Ian Lipkin
-
24. The Global Virus Network: collaboration to address pandemic and regional threats
- Prof. Sten H. Vermund
-
25. Elite controllers of HIV: from discovery to future therapies
- Prof. Bruce Walker
- Archived Lectures *These may not cover the latest advances in the field
-
26. Principles of virology I
- Prof. Richard Condit
-
27. Principles of virology II
- Prof. Richard Condit
-
28. Complex DNA viruses: herpes virus
- Dr. John Blaho
-
29. Adeno-associated viruses (AAV)
- Prof. Kenneth Berns
-
30. Poxviruses: smallpox (variola), vaccinia and monkeypox
- Prof. Paula Traktman
-
31. Can HPV testing be the sole primary cervical screening modality?
- Prof. Jack Cuzick
-
32. From viruses to oncolytics
- Prof. Roberto Cattaneo
-
33. Non HIV antivirals
- Prof. Mary Klotman
-
34. Gastroenteritis viruses
- Prof. Mary Estes
-
35. Biodefense challenges
- Dr. Connie Schmaljohn
-
37. The past, present and future of vaccination
- Prof. Stanley Plotkin
-
38. Filoviruses
- Dr. Christopher Basler
-
39. Bunyaviruses
- Prof. Richard Elliott
-
40. The immunobiology of HIV
- Prof. Norman Letvin
-
41. Hepatitis C and HCV
- Prof. Stanley Lemon
Printable Handouts
Navigable Slide Index
- Introduction
- Respiratory tract illness with unknown etiology
- Unidentified virus cytopathic effect in cell cultures
- Newly discovered paramyxovirus: EM
- Newly discovered paramyxovirus: diagnosis
- Virus identification: RAP-PCR
- Virus identification: nucleic acid purification
- Virus identification: example of RAP-PCR
- hMPV genome organization
- hMPV family tree
- hMPV seroprevalence
- hMPV genetic diversity
- hMPV antigenic diversity
- hMPV disease 1981-2001 in the Netherlands
- hMPV disease 2000-2002 in the Netherlands
- hMPV clinical 2000-2002 patient populations
- hMPV clinical 2000-2002 children
- hMPV clinical 2000-2002 demography
- hMPV clinical 2000-2002 symptoms
- hMPV clinical 2000-2002 intervention
- hMPV seasonality
- hMPV age distribution
- hMPV clinical 200-2002 prevalence
- Koch's postulates
- hMPV in cynomolgus macaques
- Rivers' modified Koch's postulates
- hMPV susceptible populations
- hMPV 20-year retrospective study
- hMPV risk groups
- Unidentifiable human coronavirus
- Human coronavirus: CPE in Vero cells
- Human coronavirus negative contrast EM
- Coronaviruses: group classification
- Human coronavirus sequence analyses
- HCoV-NL genome organisation
- HCoV-NL amino acid sequence comparison
- HCoV-NL phylogeny
- HCoV-NL prevalence in hospitalized individuals
- Patients with HCoV-NL-associated RTI
- HCoV-NL63 discoveries
- HCoV-NL63 clinical
- HCoV-HKU1 discovery
- HCoV-HKU1 phylogeny
- HCoV-HKU1 impact
- Bat coronaviruses
- Newly discovered human parvovirus: HBoV
- HBoV genetic screening
- HBoV genome organization and phylogeny
- HBoV clinical
- Emerging respiratory viruses: conclusions
Topics Covered
- Respiratory viruses
- Respiratory disease
- Virus discovery
- Koch's postulates
- Human metapneumovirus
- Human coronavirus NL63
- Human coronavirus HKU
- Human bocavirus
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Fouchier, R. (2017, May 2). Emerging respiratory viruses - discoveries between 2001 and 2005 [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 5, 2024, from https://doi.org/10.69645/WBMH2803.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Ron Fouchier has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Emerging respiratory viruses - discoveries between 2001 and 2005
A selection of talks on Microbiology
Transcript
Please wait while the transcript is being prepared...
0:00
Hello, my name is Ron Fouchier,
Virologist at Erasmus Medical Centre in Rotterdam.
In this presentation, I will discuss
the discovery and characterization of four viral pathogens that
are associated with respiratory illnesses in
humans and that have been described since 2001.
The pathogens are first a paramyxovirus named
Human metapneumovirus, two human coronaviruses,
NL63 and HKU1, and a parvovirus named Human bocavirus.
0:29
It is well known that a wide range of
pathogens can cause respiratory tract illnesses in humans.
Viruses are the most frequently detected causative agents,
in particular, 40 acute respiratory tract illnesses.
As an example, this slide shows the result of diagnostic tests for 540 patients
with respiratory problems visiting
their general practitioner about 10 years ago in the Netherlands.
Several notorious pathogens were circulating this winter season with enteroviruses,
respiratory syncytial virus, influenza A and B virus,
and rhinoviruses as the most frequently detected viral pathogens.
The reason why I put this slide up is not so much the positive diagnostic results,
which can vary considerably between studies,
but to point out that in a significant proportion of the patients,
in this case 36 percent,
no known pathogen could be detected.
This proportion of respiratory tract illnesses with unknown etiology is highly variable,
for instance, for different patient populations, locations and timing.
But in most studies like this one,
an etiological agent cannot be identified in
a large proportion of patients under investigation.
I will discuss some of the viral pathogens that have been discovered in
the past six or seven years by research groups attempting
to reduce this proportion of illnesses with unknown etiology.
In 2001, a study by the Van der Hoek and others in the Netherlands described