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Printable Handouts
Navigable Slide Index
- Introduction
- What is diabetes mellitus?
- Diabetes mellitus: model for genetic studies
- Predicted increase in diabetes incidence
- Classification of diabetes mellitus
- Genetics of diabetes mellitus
- Paradigms
- Candidate genes
- Identification of diabetes genes
- Monogenic forms of diabetes
- Human HNF-1alpha/MODY3 gene polymorphisms
- MODY-related genes and clinical phenotype
- MODY genes and pancreatic beta-cell function (1)
- Polygenic forms of diabetes
- HLA in type 1 diabetes
- Diabetes genetics and complex diseases genetics
- INS in type 1 diabetes
- Linkage analysis results summary
- Genes for type 2 diabetes
- TCF7L2 in type 2 diabetes
- Linkage mapping of type 2 diabetes
- Genome-wide association studies (1)
- Genome-wide association studies (2)
- Loci implicated in GWA
- MODY genes and pancreatic beta-cell function (2)
- Mapping determinants of human gene expression
- Allelic variation in human gene expression
- Identifying diabetes susceptibility genes
- Identifying the signature of natural selection
- Ancestral susceptibility models
- Pattern of signal shaped by LD
- Gene expression across primate species
- A virtual tsunami of data
- An optimistic view on diabetes genetics
Topics Covered
- Diabetes mellitus: definition, classification and its use as a model for genetic studies of complex disorders
- Genetic forms of diabetes mellitus: monogenic and polygenic
- Identification of diabetes genes
- Monogenic forms of diabetes: human HNF-1-alpha/MODY3 gene
- Polygenic forms of diabetes
- HLA and ISN in type 1 diabetes
- Genes for type 2 diabetes and linkage mapping
- TCF7L2 in type 2 diabetes
- Genome wide association studies and gene loci implicated in these studies
- Allelic variation in human gene expression
- Ancestral susceptibility models
Links
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Talk Citation
Cox, N. (2007, October 1). The genetic component to diabetes [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 5, 2024, from https://doi.org/10.69645/XYLS7885.Export Citation (RIS)
Publication History
Financial Disclosures
- Dr. Nancy Cox has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.