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Printable Handouts
Navigable Slide Index
- Introduction
- Questions about human population structure
- Human genome diversity cell line panel
- References
- Microsatellites
- Number of distinct alleles per locus
- Genetic variation across populations: pie charts
- Question 1: distribution of alleles
- Geographic distribution of alleles: binary table
- Geographic distribution of alleles: pie chart
- Question 2: existence of distinctive alleles
- Number of regionally private alleles per locus
- Strongly diverged alleles
- An allele private to the Americas
- Question 3: genetic similarity among populations
- Genome-wide pairwise differences
- Partition of genetic variance
- Question 4: determining geographic ancestry
- Inference of ancestry using alleles' frequencies
- Inferred population structure
- Inferred population structure viewed on a map
- Influence of the number of loci
- Influence of the numbers of loci and individuals
- Population structure for the X chromosome
- Influence of the type of marker: indels
- Inference of population ancestry
- Question 5: origin of variation across populations
- Heterozygosity and geography: simulations
- Heterozygosity and geographic distance
- The source of the human expansion
- Serial sampling model
- Serial sampling: locus TGA012
- Clines or clusters?
- Genetic and geographic distance in Asia
- Genetic and geographic distance worldwide
- Summary
Topics Covered
- Geographic distribution of genetic variants
- Private alleles
- Pairwise differences between individuals
- Partition of genetic variation
- Population structure and inference of ancestry
- Decline of heterozygosity with distance from Africa
- Serial sampling model for human evolution
- Clines and clusters
Talk Citation
Rosenberg, N. (2007, October 1). Human population structure [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 10, 2024, from https://doi.org/10.69645/VNXV7775.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Noah Rosenberg has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.