Hard tissue nanomedicine - significance of nanostructures

Published on June 30, 2015   35 min

Other Talks in the Series: Nanomedicine

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Today's topic is on Hard Tissue Nanomedicine Significance of Nanostructures. I'm Huinan Liu, from the Department of Bioengineering, at the University of California at Riverside. I am also a faculty member of our Interdisciplinary Materials Science and Engineering Program and the Bourns College of Engineering. I'm a participating faculty member of The Stem Cell Center and the Inland Empire Stem Cell Consortium, at the University of California at Riverside. If you're interested in learning more about our research, please visit our website listed on this slide.
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First I would like to give you overview of our research and multi-disciplinary collaborations. If you look at this slide, we have this big red circle. Biodegradable materials and nanostructured interfaces, which indicates our core research focus. Around it you will see the blue regions, indicate our materials of interest, starting from, for example, biodegradable metals, ceramic nanoparticles, nanocomposites of biodegradable polymers and ceramic nanoparticles, as well as how we could design and utilize nanostructured surfaces and coating for controlling cellular interactions at the interface of medical device and implants. We are interested in material design synthesis characterization, as well as implant design fabrication. Towards the right region, you will see focused areas around the regenerative medicine. In different application areas for example, bone cartilage ligament, neuro tissue regeneration, cardiovasular and neurovascular applications, neurological devices, mainly towards reducing infections in urological devices. So we are interested in developing virtual cellular models to study cellular responses to different nanostructures and different bio materials. We are also interested in how we could utilize these unique properties of materials and nanostructures, for controlling the delivery of different drugs for therapeutic purposes. So along the way, we've collaborated with clinicians and surgeons, medical device and the implant industry, as well as FDA developing in-vivo models to evaluate the bio materials and nanostructures while their functionality in functional animal models. Down the road in future, we're also interested in pre-clinical models for potential clinical translation.

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