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1. Introduction
2. Questions about genetic variation
3. How different are our genomes?
4. Serological techniques for detecting variation
5. Blood group systems in humans
6. Extreme levels of variation at HLA genes
7. Protein electroporesis
8. The rise of DNA sequence analysis
9. The human genomes...
10. The international HapMap project
11. How do we differ? let me count the ways
12. Y chromosome variation
13. Mutation is the ultimate source of variation
14. Understanding genetic variation
15. Different, but not that different
16. An aside on the genetics of race
17. Genetic variation distribution in genomes
18. Diversity isn't evenly distributed in genome (1)
19. Diversity isn't evenly distributed in genome (2)
20. Diversity isn't evenly distributed in genome (3)
21. Diversity isn't evenly distributed in genes (1)
22. Diversity isn't evenly distributed in genes (2)
23. Diversity isn't evenly distributed in genes (3)
24. Diversity isn't evenly distributed in populations (1)
25. mtDNA phylogeography
26. The colonization process: from mtDNA variation
27. The colonization process: from gut bacteria
28. Diversity isn't evenly distributed in populations (2)
29. Genetic variation: an indicator for human evolution
30. The appearance of fossil archaic forms of hominids
31. Did early humans interbreed with meanderthals
32. Haplotypes in Europeans versus non-Europeans
33. A model of human history
34. Deeper trees in the human genome
35. Highly structured ancestral populations
36. The footprints of adaptive evolution
37. Detecting recent adaptive evolution
38. Long haplotypes
39. Strong population differentiation
40. The results of the two analyses
41. Major changes in gene sequence
42. Classes of selected genes
43. Summary

Topics Covered

• The nature of genetic polymorphism
• Single nucleotide polymorphisms
• Differences between genomic regions
• Differences between populations
• Inferences about human history from genetic variation
• Detecting natural selection

Links

Series:

• Human Population Genetics I

Categories:

• Genetics & Epigenetics

Talk Citation

Publication History

• Published on October 1, 2007

Financial Disclosures

• Prof. Gil McVean has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.