Thymosin β4 coated nanofiber scaffolds for the repair of damaged cardiovascular tissue

Published on May 4, 2015   22 min

Other Talks in the Series: Nanomedicine

0:00
Good morning everyone. My name is Dr. Kumar, and I am the principal investigator and the Director of the Nanomedicine Research Laboratory in the Department of Medical Laboratory Science in the college of health University of Delaware. Today I'm going to give a talk on scaffold technology used to repair the damaged cardiovascular tissues.
0:25
After a cardiac event, the proper treatment and care of the damaged tissue is crucial in restoring the optimal cardiac function and preventing future cardiac events. Which is very difficult to achieve, so recently we have developed an approach to using very high tech tissue engineering. And in this approach, recently, we have used thymosin beta four, which we found played a very significant, vital role in cardiac health, and development by regulating angiogenesis, inflammatory responses, and wound healing. Literature has shown that the 43-amino acid protein, which is called thymosin beta 4, acts as a sequestering G-actin monomers, and subsequently effecting the actin-cytoskeletal organization necessary for the cardiac cell motility, organogenesis, and other cellular, and crucially when which is necessary for the repair of the heart.
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Thymosin β4 coated nanofiber scaffolds for the repair of damaged cardiovascular tissue

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