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Printable Handouts
Navigable Slide Index
- Introduction
- Why are we interested in skeletal variation?
- Outline of the talk
- Traditional calipers measurements
- Landmarks and virtual objects
- Outline: genetic basis of human skeletal variation
- Variation in human height
- Infinitesimal model
- Single locus model
- Two loci model
- Three loci model
- Multi-locus basis of variation in height
- Classical quantitative genetics model of heredity
- Genetic & environmental contribution to phenotypic variance
- Franz Boas
- Group variation in head (skull) shape
- Outline: 3 observations about human genetic variation
- First observation
- Partitioning variance
- Genetic differentiation of major geographic regions
- Second observation
- Relationship between genetic distance and geographic distance
- Third observation
- Expected heterozygosity and geographic distance
- Outline: cranial vs. genetic variation in humans
- Howells' present-day cranial sample
- Genetics vs. skull form
- Relationship with geographic distance
- Hanihara’s present-day cranial sample
- Within group variance & distance from Sub-Saharan Africa
- Structure of human cranial variation
- Outline: evolutionary process that shaped cranial variation
- Neutral evolutionary processes
- Nose shape vs. genetic loci
- Geographic distribution of nasal index
- Outline: comparison of humans and other taxa
- Chimpanzees species distribution in Africa
- FST comparison for humans
- FST comparison for chimpanzees
- h2 required for match
- Cranial differences between Neanderthals and humans
- Morphological split time estimator
- Split times
- Morphological split time estimates
- Summary
Topics Covered
- Quantifying human skeletal variation
- Genetic & environmental basis of human skeletal variation
- Observations about human genetic variation
- Patterns of cranial variation vs. patterns of genetic variation
- Evolutionary processes that shaped patterns of cranial variation
- Humans in comparison with other taxa
Talk Citation
Weaver, T. (2015, March 18). Genetics and human skeletal variation [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved October 8, 2024, from https://doi.org/10.69645/LQTG9011.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Timothy Weaver has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Other Talks in the Series: Human Population Genetics II
Transcript
Please wait while the transcript is being prepared...
0:00
Hi, I'm Tim Weaver.
I'm an Associate Professor of Anthropology at the University of California, Davis.
I'm also an Associated Researcher of
the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany.
In this lecture, I'm going to speak about the structure of
human skeletal variation and how the structure
relates to the structure of human genetic variation.
0:25
Studies of human skeletal variation have a long and, in some cases, infamous history.
Attempts to classify humans into races have often emphasized differences in skull form.
Many 19th and early 20th century studies of
human skeletal variation had the goal of
documenting differences between human groups in skeletal form,
particularly in skull form.
These studies were used to support racist or eugenicist agendas.
Today, most interests in
human skeletal variation is because the skeleton is the part of the phenotype
that remains from the extinct human ancestors
and close relatives that document human evolution.
When an organism dies, its tissues degrade,
but bones and teeth are quite hard,
so they withstand this degradation better than most other parts.
As a consequence, the physical record of human evolution
consists almost entirely of bones and teeth.
To put these paleontological finds in perspective,
it is necessary to understand patterns of present-day human skeletal variation.
In this context, it is also useful to study the skeletons of extant non-human primates.
This photo shows the famous paleoanthropologist, Louis Leakey,
taking a caliper measurement on a spectacular fossil skull that his wife,
Mary Leakey, also a famous paleoanthropologist,
discovered at Olduvai Gorge in Tanzania.