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Printable Handouts
Navigable Slide Index
- Introduction
- Sources of information on the history of vaccines
- The impact of vaccination
- Lady Mary Wortley Montagu
- Voltaire on variolation
- Edward Jenner
- Sarah Nelms hand
- Louis Pasteur
- Antrax vaccine
- Rabies vaccine
- Jean-Baptise Jupille at Pasteur Institute
- Daniel Elmer Salmon
- Theobald Smith
- Wilhelm Kolle
- Sir Almroth Wright
- Emil Adolf von Behring
- Pierre Paul Emile Roux
- Kitasato Shibasaburo
- Paul Ehrlich
- Jules Bordet - pertussis
- Timeline 1798-1897
- Gaston Ramon - diphtheria and tetanus
- Calmette administering oral BCG vaccination
- Max Theiler - yellow fever
- Richard Shope - influenza
- Timeline 1923-1938
- John Enders, Frederick Robbins, Thomas Weller
- Hilary Koprowski
- Dr. Jonas Salk
- Albert Sabin - polio
- John Enders and Samuel Katz - measles
- Maurice Hilleman - MMR
- Timeline 1955-1987 (1)
- Robert Austrian
- Oswald Avery
- John Robbins
- Timeline 1955-1987 (2)
- Herbert Boyer
- Stanley Cohen
- Michiaki Takahashi
- Albert Z. Kapikan - rotavirus
- Timeline 1986-2000
- Vaccines licensed since 2000
- Fred Clark and Paul Offit
- Douglas Lowy and John Schiller
- Cumulative number of vaccines developed
- Children mortality in early 19th century
Topics Covered
- History of vaccines
- The impact of vaccination
- Variolation
- Pasteur and first real vaccines
- Inactivated vaccines at the end of the 19th Century
- Toxoids
- Attenuation by serial passage
- Viruses grown in cell culture
- Genetic engineering and recombinant vaccines
- Vaccines licensed since 2000
- Cumulative number of vaccines developed
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Plotkin, S. (2015, May 28). History of vaccines [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 22, 2024, from https://doi.org/10.69645/QJXP7451.Export Citation (RIS)
Publication History
Financial Disclosures
- Stanley Plotkin consults for Sanofi, Merck, GSK, Pfizer and Takeda
Other Talks in the Series: Vaccines
Transcript
Please wait while the transcript is being prepared...
0:00
Hello. My name is Dr. Stanley Plotkin.
I am emeritus
professor of pediatrics
at the University of Pennsylvania,
and the senior editor
of the Vaccines textbook.
And I am going to talk to
you today about the history
of vaccines, which now goes
back many centuries, in fact.
0:29
So on my next slide, you have some
sources of information concerning
the history of vaccines, divided
according to whether they're brief,
medium size, or long.
The brief example is a chapter,
the first chapter from the Vaccines
textbook by my wife and myself.
The medium examples are
basically two books.
One listed is titled, Vaccines, A
Biography, edited by Artenstein.
And I also have a
book which is titled
History of Vaccine Development,
which is available from Springer.
The long history of vaccines is
a wonderful book by Herve Bazin,
which is published both
in French and in English,
and tells you everything
you ever wanted to know
about the history of vaccines.
1:35
The history of vaccination
goes back a long way.
However, the effect of
vaccination is beyond question.
As we said in the first edition
of the Vaccines textbook,
published in 1988, "The impact
of vaccination on the health
of the world's peoples
is hard to exaggerate.
With the exception of safe
water, no other modality
has had such a major
effect on mortality
reduction and population growth."
And that quotation, I
think, is indisputable.
It has been repeated often
in other publications,
usually without attribution,
but nevertheless it's
a universal truth.
The beginning of vaccination
goes back hundreds of years,
in a sense, because it began,
I think, because of the efforts
of kings and other
important people to resist
poisoning by taking small
amounts of common poisons
to build up resistance.
And so the idea of using a small
amount of something pathogenic
to protect against the
major effect of a pathogen
became a common belief.