Stem cells from adipose tissue

Published on March 5, 2014   40 min
Hello, this is Adam Katz. And the title of my presentation is "Stem Cells from Adipose Tissue." I am an associate professor in the division of plastic surgery at the University of Florida.
As part of full disclosure, I would like to mention that I am a named inventor on issued and or pending patents related to the adipose field, including adipose-derived cells and matrix. And I have in the past received royalties related to this IP. I also serve on the board of directors or have been a founder on at least two companies that operate in this field.
As a brief overview for my presentation, I will be giving a brief background on the adipose-derived cell, as well as some of the past and current science related to these cells. We'll also discuss briefly some of the regulatory issues surrounding the translation of adipose-derived cells and then the translation and commercialization of these cells specifically.
To begin, let's discuss adipose tissue, which is a tissue many of us are well aware of and have learned about in medical school or other stages of training. Many of us were taught that the function of adipose tissue was simply for storing energy and providing padding to important structures. There are two main physiological subcompartments of adipose tissue. One is the parenchyma, which is the functional part of the tissue. In this case the adipocyte, which stores energy. And surrounding this is the stroma, or the connective or supportive structural framework of a tissue. In this case, lots of fibroblasts and endothelial vascular related cells. We now know that adipose tissue in extremely complex and dynamic endocrine organ. And from our standpoint, for the purpose of this talk, we'll be talking about the regenerative potential of cells and factors that are derived from this tissue.