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Printable Handouts
Navigable Slide Index
- Introduction
- Lecture plan
- Antipsychotic drug treatment
- Major side effects of the treatment of schizophrenia
- Antipsychotic drug treatment: newer drugs
- Antipsychotic drug-induced weight gain
- Diabetes following antipsychotic treatment
- Antipsychotic drug effects on weight gain
- Weight gain studies in drug naive populations
- Antipsychotic drug-induced weight gain: questions
- Pharmacogenetic studies in schizophrenia
- Receptor mechanisms of antipsychotic weight gain
- 5-HT2C receptors and weight gain
- 5-HT2C receptors, genes and weight gain
- Pharmacogenetics of antipsychotic weight gain
- Association study of 5HT2C receptor gene: Chinese
- Expression of the Chinese study in a different way
- Association study of 5HT2C receptor gene: Spanish
- Mechanisms of the promoter polymorphism (1)
- Mechanisms of the promoter polymorphism (2)
- Olanzapine-induced weight gain
- Functional mechanisms
- Consequences of antipsychotic treatment
- Leptin
- Leptin, fat and food intake
- Leptin promoter polymorphism and weight gain
- Leptin association study
- Blood leptin and 5-HT2C genotype
- Genetic testing for drug-induced weight gain?
- Metabolic consequences - future challenges
Topics Covered
- Antipsychotic drugs: limitations and side effects
- Drug-induced weight gain
- Severity and consequences
- Receptor mechanisms
- Role of 5-HT2C receptor
- Pharmacogenetics of antipsychotic weight gain: 5-HT2C promoter polymorphism
- Functional mechanism of polymorphism
- Role of leptin and leptin-promoter polymorphism
- Role of genetic testing
- Future directions
Links
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Talk Citation
Reynolds, G. (2007, October 1). Genetic determinants of antipsychotic-induced weight gain [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 15, 2025, from https://doi.org/10.69645/JVNV2270.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Gavin Reynolds has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.