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1. Introduction
2. Symptoms of depression
3. Noradrenergic pathways in depression
4. Serotonergic pathways in normal brain
5. Serotonergic pathways in depression
6. Desirable drug - effective in all types of depression
7. Desirable features of a drug - rapid onset of action
8. Desirable features of an antidepressant
9. Psychopathology of depression and drugs used
10. Amine deficiency hypothesis
11. Neurotransmitters involved in depression
12. Treatment and adaptive changes
13. Classification of european antidepressants
14. MAO inhibitors
15. Reuptake inhibitors
16. Nonselective reuptake inhibitors
17. Selective reuptake inhibitors
18. Other antidepressants
19. Selectivity of transmitter uptake inhibitors
20. Cross-talk between the neurotransmitters
21. Sites of action of tricyclics on neuron
22. Sites of action of MAO inhibitors
23. Electroconvulsive shock therapy

Topics Covered

• Noradrenergic pathways in depression
• Serotonergic pathways in normal brain and in depression
• Desirable features of an antidepressant
• Drugs used in the treatment of depression
• Classification of antidepressants
• Tricyclic antidepressants and monoamine
• Oxidase inhibitors: sites of action
• The relationship between pre- and post-synaptic structures
• Electroconvulsive shock therapy

Links

Series:

• Psychopharmacogenetics

Categories:

• Neuroscience
• Pharmaceutical Sciences

Therapeutic Areas:

• Neurology

Talk Citation

Publication History

• Published on October 1, 2007

Financial Disclosures

• Prof. Brian Leonard has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.