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Printable Handouts
Navigable Slide Index
- Introduction
- Description of diabetes
- Symptoms of diabetes
- Criteria for screening
- Three challenges for diabetes
- Abbreviated history of diabetes diagnosis
- Glucose distribution is unimodal (1)
- Glucose distribution is unimodal (2)
- Glucose distribution in Pima Indians
- Cutoff values - mathematical manipulations
- Different classifications for diagnosis of diabetes
- Where to draw the line?
- NDDG & WHO criteria for diabetes diagnosis (1)
- NDDG & WHO criteria for diabetes diagnosis (2)
- NDDG & WHO criteria for diabetes diagnosis (3)
- Important caveat
- WHO criteria for diabetes mellitus
- The expert committee
- Relationship between FPG & 2hr value on OGTT
- FPG cutpoints
- Decisions of the expert committee
- Glycation
- Prevalence of retinopathy in Pima Indians
- Pima Indians study
- Prevalence of retinopathy in NHANES III
- The NHANES III study
- Prevalence of retinopathy in Egyptians
- The Egyptian study
- Reproducibility of the OGTT
- Oral glucose tolerance tests
- Quantitation of variation
- Repeated results of 2hr glucose test
- Reproducibility of diagnosis by OGTT (1)
- Reproducibility of diagnosis by OGTT (2)
- Reproducibility of diagnosis by OGTT (3)
- Using HbA1c levels to diagnose diabetes
- Expert committee on diagnosis of diabetes
- The HbA1c assay advantages
- Repeated results of HbA1c test
- Repeated results of FPG test
- HbA1c is recommended for diagnosis of diabetes
- Prevalence of retinopathy and HbA1c levels
- ADA criteria for the diagnosis of diabetes
- Screening for diabetes before 2010
- ADA recommendations - FPG or HbA1c
- Thank you
Topics Covered
- Description & symptoms of diabetes
- Criteria for screening and challenges
- Abbreviated history of diabetes diagnosis
- Glucose distribution (unimodal & bimodal)
- Cutoff values & mathematical manipulations
- Different criteria for diagnosis of diabetes & diabetes classifications
- WHO criteria for diabetes mellitus
- Relationship between FPG & 2hr value on OGTT
- Decisions of the expert committee – Glycation
- The Pima Indians, Egyptian, and NHANES III studies
- Prevalence of retinopathy
- Oral glucose tolerance tests
- Quantitation of variation
- Using HbA1c levels to diagnose diabetes
- Expert committee on diagnosis of diabetes
- Screening for diabetes before and after 2010 ADA criteria and recommendations for diabetes diagnosis
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Davidson, M. (2021, September 30). Evolution of diagnostic criteria for diabetes [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved November 21, 2024, from https://doi.org/10.69645/QVLR5198.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Mayer Davidson has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
A selection of talks on Metabolism & Nutrition
Transcript
Please wait while the transcript is being prepared...
0:00
This is Dr. Mayer B. Davidson.
I am a Professor of Medicine at
the Charles R. Drew University
and the David Geffen
School of Medicine at UCLA.
And today I will be talking
to you about the evolution
of the diagnostic
criteria for diabetes.
0:20
To make sure that
we're on the same page,
I first will give you a
description of diabetes.
It's a metabolic disorder,
which is characterized by having
elevated blood
glucose, and you often
hear the term blood sugar levels.
Associated with this are small
blood vessel complications.
And these complications affect
the eyes, and the kidneys,
and the peripheral nerves.
In addition, there are complications
affecting the large blood vessels.
And they cause heart
attacks, strokes,
and peripheral arterial disease--
That is the vessels that go
into the legs often get clogged.
0:58
Usually, people with diabetes
have no symptoms of it.
The exceptions are that if
the blood sugar is very high
they will have increased
urination and increased thirst,
and maybe even some
blurring of vision.
Also, if they have the advanced
complications that I mentioned
on the previous
slide, they will have
the symptoms of those complications.
But since most people
don't have symptoms,
the first and important
step in diagnosing diabetes
is to screen for it in
people at high risk.
Some examples of those individuals
are those who are obese,
those who have a positive family
history in first degree relatives--
That is people whose parents have
diabetes, whose brothers or sisters
have diabetes, or
children have diabetes--
this is in type 2 diabetes
we're talking about here--
and those who have
high blood pressure.