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Printable Handouts
Navigable Slide Index
- Introduction
- What do this people have in common?
- Fight tuberculosis
- TB mortality and disease rates in Netherlands
- TB incidence
- Lecture structure
- 1. Natural history of TB disease
- Disease manifestations
- Predominant clinical presentations by age
- Effect of CD4 count on clinical presentation
- Incubation period
- Survival of untreated TB
- 2. Progression from latent TB to disease
- Latent TB infection
- Risk of TB disease is age dependent
- Risk factors for progression to TB disease
- HIV
- Malnutrition
- Diabetes
- Tobacco smoking
- 4. Transmission, infection and re-infection
- Risk factors for TB transmission
- TB transmission
- Effect of UV light on transmission risk
- Infectious aerosols and sputum smear grade
- Infectiousness and smear status
- Closeness of contact and TB transmission
- Paris, 1910
- Duration of infectiousness
- Re-infection
- 4. Quantifying the burden of TB
- Measures of disease occurrence: incidence
- Measures of disease occurrence: prevalence
- Incidence and prevalence
- Incidence, prevalence and notification rate
- Deriving incidence from prevalence
- Annual risk of TB infection (ARTI)
- Styblo's rule
- Styblo's rule: still valid?
- Styblo's rule refuted
- Case detection rate (CDR)
- HIV reduces the duration of TB disease
Topics Covered
- Global distribution of tuberculosis
- Natural history
- Risk factors for progression from latent infection to tuberculosis disease
- Transmission, infection and re-infection
- Quantifying the burden of tuberculosis in human populations
- Impact of HIV on tuberculosis epidemiology
Links
Series:
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Therapeutic Areas:
Talk Citation
Cobelens, F. (2013, February 28). Basics of tuberculosis epidemiology [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 15, 2025, from https://doi.org/10.69645/MKVM7927.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Frank Cobelens has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.