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Printable Handouts
Navigable Slide Index
- Introduction
- Heart failure: the problem
- Hospitalization and Congestive Heart Failure (CHF)
- Heart failure hospitalizations
- The predominant contributor to heart failure costs
- Mortality in heart failure trials
- Reasons for increased heart failure
- Process of heart failure progression
- Cycle of heart failure progression
- Medical therapies for heart failure
- Current treatment of CHF with systolic dysfunction
- Number of heart transplants worldwide
- FDA indications for LVAD usage
- Stem cells in the future treatment of heart failure
- Stem cells
- CD34 positive stem cells
- CD34+ cells differentiation into cardiomyocytes
- Repair of infarcted myocardium by stem cells
- Procedure of cells transplantation
- Improvement in myocardial perfusion
- Transplantation of progenitor cells
- Assay of the left ventricular function
- Evaluation of wall motion
- Autologous of bone marrow cell transplantation
- The NOGA myostar injection catheter
- Injection catheter technique
- SPECT and electromechanical map analysis
- Hemodynamic data summary
- Angiographic and EMM results
- Infarct remodeling after progenitor cell treatment
- Ejection fraction and end diastolic volume
- Initial and follow-up results in endsystolic volumes
- Evaluation of wall motion
- Intracoronary autologous bone marrow cell transfer
- Global LVEF at baseline and 6 months follow-up
- Subgroup analysis of global LVEF changes
- Comparison of SMs and CD133+ progenitors
- LVEF ejection fraction
- Emax comparison
- Transendocardial injection of ABMM
- Number of capillaries
- Trichrome stain of the heart walls
- Improved exercise capacity and ischemia
- MSCs differentiate into endothelial phenotype
- Ejection fraction at rest and with stress
- Fibrosis and vascular density comparison
- Dil staining of the anterior and posterior walls
- Stem cells in the treatment of heart disease
- Use of mouse ESC to infarcted sheep myocardium
- CD133+ cells enhance myocardium function
- Embryonic versus adult stem cells
- Conclusions
- Texas heart institute
Topics Covered
- Heart failure: the problem
- Reasons for increased heart failure
- Current medical treatment of Congestive Heart Failure with systolic dysfunction
- Stem cells in the future treatment of heart failure
- Stem cell reservoirs
- Types of stem cells currently under study
Links
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Talk Citation
Willerson, J. (2007, October 1). Stem cell therapy for the treatment of heart failure [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved October 7, 2024, from https://doi.org/10.69645/PZTA5076.Export Citation (RIS)
Publication History
Financial Disclosures
- Dr. James Willerson has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.