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Printable Handouts
Navigable Slide Index
- Introduction
- Outline
- FEV1 decline and disability
- Decline of FEV1 in COPD
- Symptomatic COPD: natural history?
- New evidence
- Physical activity in COPD
- Health-related quality of life scores
- A question arises
- Inflammation in the early stages of COPD
- Small-airway obstruction and emphysema
- Pathophysiology of mild COPD
- Mechanisms of air trapping (1)
- Cross-sectional study
- Natural history of lung hyperinflation in COPD
- COPD challenge test
- Cardiopulmonary exercise testing
- Exertional dyspnea intensity
- Exercise responses in symptomatic COPD
- Ventilatory response to exercise
- Ventilation-perfusion imbalance in COPD
- Operating lung volumes during exercise
- The importance of dynamic lung hyperinflation
- Respiratory mechanical measurements
- Esophageal pressure and flow tracings
- Respiratory muscle pressures during exercise (1)
- The continuum of COPD
- Respiratory muscle pressures during exercise (2)
- Dyspnea with increasing COPD severity
- Intensity and quality of dyspnea
- Progressive neuromechanical dissociation
- Operating lung volumes during exercise (1)
- Sensory-mechanical relations during exercise (1)
- Sensory-mechanical relations during exercise (2)
- Respiratory mechanics at the limits of tolerance
- Evolution of dyspnea during exercise in COPD
- Neuromechanical coupling and dissociation
- Conclusions (1)
- Conclusions (2)
- Improving dyspnea and activity restriction
- Pharmacological volume reduction
- Lung hyperinflation and its reversibility
- Bronchodilator responsiveness
- Mechanisms of air trapping (2)
- Pulmonary function post ipratropium bromide
- Impact of acute anticholinergic therapy
- Mechanical measurements during exercise
- Operating lung volumes during exercise (2)
- Effects of lung volume deflation
- IC response to long-acting bronchodilators
- Improvements in respiratory mechanics
- Responses to bronchodilators in COPD
- Conclusions (3)
- Clinical course of COPD (1)
- Clinical course of COPD (2)
Topics Covered
- Evolution of respiratory impairments from mild to sever COPD
- Progression of the symptoms of COPD: dyspnea and exercise impairment
- Mechanism s of progression
- Optimizing respiratory mechanics
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Talk Citation
O'Donnell, D. (2012, July 31). The continuum of COPD: a physiological perspective [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved October 5, 2024, from https://doi.org/10.69645/KDWY9261.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Denis O'Donnell has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.