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• 42 min
  1. Historic introduction to innate immunity

  • Prof. Heiko Herwald
  • Prof. Arne Egesten
• 52 min
  2. Evolution of innate immunity

  • Prof. Jim Kaufman
• 25 min
  3. The phagocytic synapse in distinguishing particulate and soluble stimuli

  • Prof. David Underhill
• 23 min
  4. How bacterial pathogens avoid phagocyte killing

  • Dr. Thomas Areschoug
• 43 min
  5. Origin of myeloid cells

  • Prof. Frederick A. Geissmann
• 67 min
  6. Dendritic cells

  • Prof. Muriel Moser
• 38 min
  7. Eosinophil biology and disorders associated with eosinophilia

  • Dr. Thomas B. Nutman
• 60 min
  8. CD1d-restricted NKT cells: regulators of inflammation and autoimmunity

  • Prof. Steven A. Porcelli
• 50 min
  9. Innate-like B cells

  • Prof. John F. Kearney
• 58 min
  10. Cytoplasmic innate immune sensors

  • Prof. Seth Masters
• 76 min
  11. An introduction to the interleukin-1 family of cytokines

  • Dr. John Sims
• 28 min
  12. The role of myeloid cells in HIV associated immune reconstitution inflammatory syndrome

  • Prof. Robert Wilkinson
  • Prof. Graeme Meintjes
• 37 min
  13. Antimicrobial peptides in the innate immune system of the lung

  • Prof. Dr. Pieter S. Hiemstra
• 49 min
  14. Chemokines and their receptors: their biology and therapeutic relevance

  • Dr. Amanda Proudfoot
• 45 min
  15. Heat shock proteins and their role in the immune regulation of inflammation

  • Prof. Willem Van Eden
• 42 min
  16. Tissue damage control confers host tolerance to infection

  • Dr. Miguel P. Soares
• 22 min
  17. Autophagy as a barrier to infection

  • Prof. Michele Swanson
• 42 min
  18. Innate immunity in the intestine in health and disease

  • Prof. Kevin Maloy
• 51 min
  19. Dendritic cells and the eye: their role in the ocular immune response

  • Prof. John V. Forrester
• 26 min
  20. Mononuclear phagocytes and HIV infection

  • Dr. Guido Poli
• 41 min
  21. Th17 cells and innate immunity

  • Prof. Mihai Netea
• 37 min
  22. Epigenetic regulation of innate immunity

  • Dr. Osamu Takeuchi
• 66 min
  23. Intracellular DNA sensing pathways

  • Prof. Veit Hornung
• 52 min
  24. Physiology of innate immunity

  • Prof. Keith W. Kelley
• 49 min
  25. Innate immunity in the genitourinary tract: genetics of susceptibility to disease or asymptomatic carriage

  • Prof. Catharina Svanborg
• 32 min
  26. Regulation of type 2 immunity by basophils

  • Prof. David Voehringer
• Archived Lectures *These may not cover the latest advances in the field
• 53 min
  27. TLRs, NLRs, DAMPs and PAMPs

  • Prof. Luke O'Neill

Printable Handouts

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Navigable Slide Index

1. Introduction
2. The toll of infectious diseases
3. The golden age of microbiology
4. How do we kill bacteria?
5. Innate immunity
6. Ilya Metchnikov
7. Toll is important for host defense
8. The Toll-like receptor signal pathway
9. TLRs as pattern recognition receptors
10. Adaptive immunity
11. Innate versus specific immunity
12. The host defense to an infection
13. Th1/Th2 hypothesis and EAE
14. IL-12R vs. IL-23R
15. A new T-helper subset
16. IL-1 and IL-23 drive differentiation of human TH17
17. IL-1 and PGE2 drive differentiation of human TH17
18. A new T-helper subset
19. IL-17 family members
20. The roles of IL-17A and IL-17F
21. The roles of IL-17E
22. IL-22 induces production of defensins
23. Th17 responses in inflammation
24. Are Th17 responses important in humans?
25. Hyper IgE syndrome (1)
26. IFN gamma defect in HIES
27. Th17 populations in HIES
28. Genetic cause: STAT3 mutations
29. Hyper IgE syndrome (2)
30. Autosomal dominant CMC
31. Chronic mucocutaneous candidiasis (1)
32. Chronic mucocutaneous candidiasis (2)
33. Chronic mucocutaneous candidiasis (3)
34. Chronic mucocutaneous candidiasis (4)
35. STAT1 mutation in the CC domain
36. Summary
37. Cunclusions
38. Acknowledgements

Topics Covered

• Resistance to infection
• Involvement of innate and adaptive immune responses
• Innate immunity modulates Th-responses
• Th17 are crucial for mucosal host defense
• Deficiencies in Th17 in patients lead to mucosal fungal and bacterial infections

Links

Series:

• Cells of the Innate Immune System

Categories:

• Immunology

Therapeutic Areas:

• Immunology & Inflammation

Talk Citation

Publication History

• Published on April 3, 2012

Financial Disclosures

• Prof. Mihai Netea has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.